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[自身免疫性疾病自体干细胞移植的动员与预处理方案实施：MATHEC-SFGM-TC指南]

[Mobilization and conditioning protocols actualization for autologous stem cell transplantation for autoimmune diseases: Guidelines from MATHEC-SFGM-TC].

作者信息

Bonnin Agnès, Terriou Louis, Beuvon Clément, Tudesq Jean-Jacques, Puyade Mathieu, Pugnet Grégory, Maria Alexandre, Llorente Cristina Castilla, Lansiaux Pauline, Cacciatore Carlotta, Badoglio Manuela, Yakoub-Agha Ibrahim, Farge-Bancel Dominique, Marjanovic Zora

机构信息

AP-HP, hôpital Saint-Antoine, service d'hématologie clinique et thérapie cellulaire, 184, rue du Faubourg Saint-Antoine, 75012 Paris, France.

CHU de Lille, département de médecine interne et immunologie clinique, 59000 Lille, France; Centre de référence des maladies auto-immunes et auto-inflammatoires rares (CERAINO), 59000 Lille, France.

出版信息

Bull Cancer. 2024 Feb;111(2S):S84-S95. doi: 10.1016/j.bulcan.2023.09.002. Epub 2023 Oct 14.

DOI:10.1016/j.bulcan.2023.09.002
PMID:37845095
Abstract

The Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) organized the 13th workshop on hematopoietic stem cell transplantation clinical practices harmonization procedures in September 2022 in Lille, France. The aim of this workshop is to update the mobilization and conditioning protocols for autologous hematopoietic stem cell transplantation for autoimmune diseases, and to specify contraindications for transplant, conditioning regimen selection, immunosuppressive treatment discontinuation before mobilization and disease-specific surveillance.

摘要

法语国家骨髓移植与细胞治疗协会（SFGM-TC）于2022年9月在法国里尔组织了第13次造血干细胞移植临床实践协调程序研讨会。本次研讨会的目的是更新自身免疫性疾病自体造血干细胞移植的动员和预处理方案，并明确移植的禁忌症、预处理方案选择、动员前免疫抑制治疗的停用以及疾病特异性监测。

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引用本文的文献

1
T-cell Recovery After Autologous Hematopoietic Stem Cell Transplantation in Autoimmune Diseases.自身免疫性疾病自体造血干细胞移植后的T细胞恢复
Adv Exp Med Biol. 2025;1471:301-323. doi: 10.1007/978-3-031-77921-3_12.
2
Innovative cellular therapies for autoimmune diseases: expert-based position statement and clinical practice recommendations from the EBMT practice harmonization and guidelines committee.自身免疫性疾病的创新细胞疗法：欧洲血液与骨髓移植协会实践协调与指南委员会基于专家的立场声明和临床实践建议
EClinicalMedicine. 2024 Feb 10;69:102476. doi: 10.1016/j.eclinm.2024.102476. eCollection 2024 Mar.