Celik C, Venditti J A, Satchidanand S, Freier D T
J Surg Oncol. 1986 Dec;33(4):268-72. doi: 10.1002/jso.2930330414.
Polypoid epithelial tumors of the duodenum and ampulla of Vater are rarely diagnosed preoperatively without wide application of fiberoptic endoscopy. The symptoms are nonspecific. Only a high index of suspicion will lead to early diagnosis. Life-threatening complications and increased incidence of malignant transformations are associated with delayed diagnosis. This paper reviews 11 patients (nine previously unreported) with villous tumor of the ampulla of Vater and two with this neoplasm in the duodenum. It also reviews the important principles of management illustrated by the behavior of the tumors of these 11 patients compared to those of previous reports. For favorable results, all lesions must be excised in toto and evidence of invasive malignancy must lead to aggressive treatment whenever feasible.
十二指肠和 Vater 壶腹的息肉样上皮肿瘤，若不广泛应用纤维内镜，术前很少能得到诊断。其症状不具特异性。只有高度怀疑才能实现早期诊断。延迟诊断会导致危及生命的并发症以及恶变发生率增加。本文回顾了 11 例 Vater 壶腹绒毛状肿瘤患者（9 例此前未报道）以及 2 例十二指肠该肿瘤患者。还回顾了与既往报道相比，这 11 例患者肿瘤表现所阐明的重要治疗原则。为取得良好效果，所有病变均须完整切除，一旦有浸润性恶性肿瘤的证据，只要可行，就必须积极治疗。
