Stern Benjamin, Chowers Itay, Ben-Eli Hadas
Department of Ophthalmology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Department of Optometry and Vision Science, Hadassah Academic College, Jerusalem, Israel.
Eur J Ophthalmol. 2024 May;34(3):759-765. doi: 10.1177/11206721231207470. Epub 2023 Oct 18.
This study investigates the relationship between pupil size during biometry examinations and the chord mu value in candidates for cataract surgery.
Retrospective analysis of ocular biometry measurements was performed on consecutive cataract surgery candidates above 50 years of age, examined between 2018 and 2020 at a single tertiary referral center. Statistical analysis assessed the association between pupil size and the chord mu value. The population was categorized into groups based on pupil size, and an analysis was conducted on the barycenter positions of the iris and pupil center for each group.
The analysis included 2877 patients. A weak positive correlation was observed between the chord mu value and pupil size using Pearson's test ( = 0.160, < 0.01). Group stratification by pupil size indicated temporal and inferior shifts in pupil center barycenter as pupil size increased, reflecting asymmetrical pupil dilation during mydriasis. A moderate positive correlation between the chord mu value and chord alpha value was identified (Pearson's test, = 0.641, < 0.01). As expected, no correlation was found between chord alpha value and pupil size.
Chord mu values were higher in patients with mydriatic pupils, likely due to asymmetric pupil dilation and center displacement. Evaluating chord mu values requires considering pupil status and conducting biometry under standardized lighting to prevent misinterpretation caused by pharmacological dilation. This caution is crucial to avoid erroneously excluding eligible patients from multifocal IOL implants. Alternatively, the chord alpha value could serve as a more appropriate alternative in such scenarios.
本研究调查白内障手术候选者生物测量检查期间瞳孔大小与弦μ值之间的关系。
对2018年至2020年在单一三级转诊中心接受检查的连续50岁以上白内障手术候选者的眼部生物测量数据进行回顾性分析。统计分析评估瞳孔大小与弦μ值之间的关联。根据瞳孔大小将人群分组，并对每组虹膜和瞳孔中心的重心位置进行分析。
分析纳入2877例患者。使用Pearson检验观察到弦μ值与瞳孔大小之间存在弱正相关（r = 0.160，P < 0.01）。按瞳孔大小进行组分层显示，随着瞳孔大小增加，瞳孔中心重心出现颞侧和下方移位，反映散瞳期间瞳孔扩张不对称。确定弦μ值与弦α值之间存在中度正相关（Pearson检验，r = 0.641，P < 0.01）。正如预期的那样，未发现弦α值与瞳孔大小之间存在相关性。
散瞳患者的弦μ值较高，可能是由于瞳孔扩张不对称和中心移位所致。评估弦μ值需要考虑瞳孔状态，并在标准化照明下进行生物测量，以防止药物散瞳引起的错误解读。这种谨慎对于避免错误地将符合条件的患者排除在多焦点人工晶状体植入之外至关重要。或者，在这种情况下，弦α值可能是更合适的替代指标。
