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[Relationship between perazine serum concentration and clinical results in long-term treated schizophrenic outpatients (author's transl)].

作者信息

Pietzcker A, Müller-Oerlinghausen B, Schley J, Chaskel H, Poppenberg A, Urban R

出版信息

Arzneimittelforschung. 1978;28(8):1302-3.

PMID:37850
Abstract

The perazine serum concentration was determined with a new gaschromatographic method in 33 schizophrenic outpatients of our psychiatric catamnestic unit who had received perazine for a period of 18 years. A very high constancy of the perazine serum level could be demonstrated by repeated measurements. A close connection existed between perazine dosage and perazine serum level. Both findings suggest a very good complicance of these patients. Serum levels were correlated positively with the intensity of the psychopathologic symptoms as well as with the frequency of side-effects, particularly with slight changes of liver enzymes.

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