Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Institute for Life Course and Aging, University of Toronto, Toronto, Ontario, Canada.
PLoS One. 2023 Oct 18;18(10):e0289932. doi: 10.1371/journal.pone.0289932. eCollection 2023.
The COVID-19 pandemic and associated public health measures have exacerbated many known risk factors for depression that may be particularly concerning for individuals with chronic health conditions, such as peptic ulcer disease (PUD). In a large longitudinal sample of older adults with PUD, the current study examined the incidence of depression during the pandemic among those without a pre-pandemic history of depression (n = 689) and the recurrence of depression among those with a history of depression (n = 451). Data came from four waves of the Canadian Longitudinal Study on Aging (CLSA). Multivariate logistic regression analyses were conducted to identify factors associated with incident and recurrent depression. Among older adults with PUD and without a history of depression, approximately 1 in 8 (13.0%) developed depression for the first time during the COVID-19 pandemic. Among those with a history of depression, approximately 1 in 2 (46.6%) experienced depression during the pandemic. The risk of incident depression and recurrent depression was higher among those who were lonely, those with functional limitations, and those who experienced an increase in family conflict during the pandemic. The risk of incident depression only was higher among women, individuals whose income did not satisfy their basic needs, those who were themselves ill and/or those whose loved ones were ill or died during the pandemic, and those who had disruptions to healthcare access during the pandemic. The risk of recurrent depression only was higher among those with chronic pain and those who had difficulty accessing medication during the pandemic. Implications for interventions are discussed.
新冠疫情和相关的公共卫生措施加剧了许多已知的抑郁症风险因素，这些因素可能对患有慢性疾病的人，如消化性溃疡病（PUD），尤其令人担忧。在一项针对患有 PUD 的老年人大样本的纵向研究中，本研究调查了在没有疫情前抑郁症病史的人群（n=689）中，疫情期间抑郁症的发病率，以及在有抑郁症病史的人群（n=451）中抑郁症的复发率。数据来自加拿大老龄化纵向研究（CLSA）的四个波次。采用多变量逻辑回归分析来确定与新发和复发性抑郁症相关的因素。在患有 PUD 且没有抑郁症病史的老年人中，约有 1/8（13.0%）的人在 COVID-19 大流行期间首次出现抑郁症。在有抑郁症病史的人群中，约有 1/2（46.6%）的人在疫情期间经历了抑郁症。在孤独、存在功能限制和家庭冲突加剧的人群中，新发和复发性抑郁症的风险更高。新发抑郁症的风险仅在女性、收入无法满足基本需求、自身患病和/或亲人在疫情期间患病或死亡、以及疫情期间医疗服务中断的人群中更高。复发性抑郁症的风险仅在存在慢性疼痛和在疫情期间难以获得药物的人群中更高。讨论了干预措施的意义。
