Fowler Flávio A, Yabumoto Cristina, Osaki Midori H, Gameiro Gustavo R, Brabo Janaina L, Matayoshi Suzana, Marinho Regina C R S, Osaki Tammy H
Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Department of Ophthalmology, Universidade de São Paulo, São Paulo, SP, Brazil.
Arq Bras Oftalmol. 2023 Oct 13;87(6):e20220160. doi: 10.5935/0004-2749.2022-0160. eCollection 2023.
Information is scarce regarding the comprehensive profile of patients with essential blepharospasm and hemifacial spasm in Brazil. The present study aimed to assess the clinical features of patients with these conditions, followed up in two reference centers in Brazil.
The study included patients with essential blepharospasm and hemifacial spasm, followed up at the Departments of Ophthalmology at Universidade Federal de São Paulo and Universidade de São Paulo. Apart from demographic and clinical features, past stressful events related to the first symptoms (triggering event), aggravating factors, sensory tricks, and other ameliorating factors for the eyelid spasms were assessed.
A total of 102 patients were included in this study. Most patients were female (67.7%). Essential blepharospasm was the most frequent movement disorder [51/102 patients (50%)], followed by hemifacial spasm (45%) and Meige's syndrome (5%). In 63.5% of the patients, the onset of the disorder was associated with a past stressful event. Ameliorating factors were reported by 76.5% of patients; 47% of patients reported sensory tricks. In addition, 87% of the patients reported the presence of an aggravating factor for the spasms; stress (51%) was the most frequent.
Our study provides information regarding the clinical features of patients treated in the two largest ophthalmology reference centers in Brazil.
关于巴西特发性眼睑痉挛和半面痉挛患者的综合情况，相关信息匮乏。本研究旨在评估在巴西两个参考中心接受随访的这些疾病患者的临床特征。
该研究纳入了在圣保罗联邦大学和圣保罗大学眼科接受随访的特发性眼睑痉挛和半面痉挛患者。除人口统计学和临床特征外，还评估了与首发症状相关的既往应激事件（触发事件）、加重因素、感觉技巧以及眼睑痉挛的其他缓解因素。
本研究共纳入102例患者。大多数患者为女性（67.7%）。特发性眼睑痉挛是最常见的运动障碍[51/102例患者（50%）]，其次是半面痉挛（45%）和梅杰综合征（5%）。在63.5%的患者中，疾病发作与既往应激事件有关。76.5%的患者报告了缓解因素；47%的患者报告了感觉技巧。此外，87%的患者报告存在痉挛的加重因素；压力（51%）是最常见的。
我们的研究提供了关于在巴西两个最大的眼科参考中心接受治疗的患者临床特征的信息。
