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Characteristics and outcomes of patients with CLL and CDKN2A/B deletion by fluorescence in situ hybridization.

作者信息

Teierle Samantha M, Huang Ying, Kittai Adam S, Bhat Seema A, Grever Michael, Rogers Kerry A, Zhao Weiqiang, Jones Daniel, Byrd John C, Avenarius Matthew R, Heerema Nyla A, Woyach Jennifer A, Miller Cecelia R

机构信息

Division of Hematology, Comprehensive Cancer Center, The Ohio State University, Columbus, OH.

Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH.

出版信息

Blood Adv. 2023 Dec 12;7(23):7239-7242. doi: 10.1182/bloodadvances.2023010753.

DOI:10.1182/bloodadvances.2023010753
PMID:37851900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10698542/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c193/10698542/a2aa3fac36da/BLOODA_ADV-2023-010753-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c193/10698542/a2aa3fac36da/BLOODA_ADV-2023-010753-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c193/10698542/a2aa3fac36da/BLOODA_ADV-2023-010753-gr1.jpg

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Nat Med. 2023 Jan;29(1):158-169. doi: 10.1038/s41591-022-02113-6. Epub 2023 Jan 9.
2
The impact of increasing karyotypic complexity and evolution on survival in patients with CLL treated with ibrutinib.伊布替尼治疗的 CLL 患者中核型复杂性和演变对生存的影响。
Blood. 2021 Dec 9;138(23):2372-2382. doi: 10.1182/blood.2020010536.
3
B-cell receptor signaling and genetic lesions in TP53 and CDKN2A/CDKN2B cooperate in Richter transformation.
伴有复杂核型的慢性淋巴细胞白血病患者的管理策略
Br J Haematol. 2025 Mar;206(3):832-841. doi: 10.1111/bjh.19986. Epub 2025 Jan 6.
4
Molecular Subtypes and the Role of TP53 in Diffuse Large B-Cell Lymphoma and Richter Syndrome.分子亚型及TP53在弥漫性大B细胞淋巴瘤和里氏综合征中的作用
Cancers (Basel). 2024 Jun 7;16(12):2170. doi: 10.3390/cancers16122170.
B 细胞受体信号转导以及 TP53 和 CDKN2A/CDKN2B 的遗传病变在里希特转化中共同作用。
Blood. 2021 Sep 23;138(12):1053-1066. doi: 10.1182/blood.2020008276.
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Revisiting Richter transformation in the era of novel CLL agents.重新审视新型 CLL 药物时代的 Richter 转化。
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