Center for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation, Arizona State University, USA.
Center for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation, Arizona State University, USA; Ivy Center for Family Wellness, The Society of St Vincent de Paul, USA.
Contemp Clin Trials. 2023 Dec;135:107361. doi: 10.1016/j.cct.2023.107361. Epub 2023 Oct 16.
Latino families are disproportionately affected by type 2 diabetes (T2D) and lifestyle intervention is the first-line approach for preventing T2D. The purpose of this study is to test the efficacy of a culturally-grounded lifestyle intervention that prioritizes health promotion and diabetes prevention for Latino families. The intervention is guided by a novel Family Diabetes Prevention Model, leveraging the family processes of engagement, empowerment, resilience, and cohesion to orient the family system towards health.
Latino families (N = 132) will be recruited and assessed for glucose tolerance as measured by an Oral Glucose Tolerance Test (OGTT) and General and Weight-Specific Quality of Life (QoL) at baseline, four months, and 12 months. All members of the household age 10 and over will be invited to participate. Families will be randomized to the intervention group or a control group (2:1). The 16-week intervention includes weekly nutrition and wellness classes delivered by bilingual, bicultural Registered Dietitians and community health educators at a local YMCA along with two days/week of supervised physical activity classes and a third day of unsupervised physical activity. Control families will meet with a physician and a Registered Dietitian to discuss the results of their metabolic testing and recommend lifestyle changes. We will test the efficacy of a family-focused diabetes prevention intervention for improving glucose tolerance and increasing QoL and test for mediators and moderators of long-term changes.
This study will provide much needed data on the efficacy of a family-focused Diabetes Prevention Program among high-risk Latino families.
拉丁裔家庭受到 2 型糖尿病（T2D）的影响不成比例，生活方式干预是预防 T2D 的首选方法。本研究的目的是测试一种文化上根植的生活方式干预的疗效，该干预优先促进健康和预防糖尿病拉丁裔家庭。该干预措施由一种新颖的家庭糖尿病预防模型指导，利用参与、赋权、弹性和凝聚力等家庭过程，使家庭系统向健康方向发展。
将招募拉丁裔家庭（N=132），并通过口服葡萄糖耐量试验（OGTT）和一般和体重特异性生活质量（QoL）评估其葡萄糖耐量，基线、四个月和 12 个月时进行评估。邀请所有年满 10 岁及以上的家庭成员参加。家庭将随机分为干预组或对照组（2:1）。为期 16 周的干预包括每周由双语、双文化注册营养师和社区健康教育者在当地基督教青年会（YMCA）提供的营养和健康课程，以及两天/周的监督体育锻炼课程和第三天的非监督体育锻炼。对照组家庭将与医生和注册营养师会面，讨论他们的代谢测试结果，并建议改变生活方式。我们将测试以家庭为中心的糖尿病预防干预在改善葡萄糖耐量和提高生活质量方面的疗效，并测试长期变化的中介和调节因素。
本研究将为高危拉丁裔家庭中以家庭为中心的糖尿病预防计划的疗效提供急需的数据。
