Phillips Y Y, Lonigan R M, Joyner L R
Crit Care Med. 1979 Aug;7(8):351-3. doi: 10.1097/00003246-197908000-00007.
The development of a bronchopleural fistula (BPF) is an infrequent, but potentially devastating complication of positive pressure ventilation. A case report is detailed in which a BPF arose in a patient on controlled ventilation with a PEEP of 22 cm H2O. Within 12 hours, fistula flow was continuous and accounted for 75% of the delivered tidal volume. PEEP fell rapidly during expiration; oxygenation steadily deteriorated as the aAO2 fell 0.27 to 0.14. Conventional treatment methods were unsuccessful, and a system was constructed for adding controlled levels of positive pressure ot the pleural space on the side of the BPF. By decreasing the expiratory transpulmonary pressure difference (PEEP minus pleural pressure), the fistula leak was greatly decreased, and PEEP and oxygenation were stabilized. This system can be rapidly constructed at the bedside with equipment routinely available in most hospitals and offers the ability to adjust the expiratory transpulmonary pressure, lung volume, and BPF flow while maintaining positive pressure ventilation with PEEP.
支气管胸膜瘘(BPF)的发生是正压通气中一种罕见但可能具有毁灭性的并发症。本文详细报告了一例在接受22 cm H2O呼气末正压(PEEP)控制通气的患者中出现BPF的病例。在12小时内,瘘口持续有气流,占潮气量的75%。呼气时PEEP迅速下降;随着动脉血氧含量(aAO2)从0.27降至0.14,氧合功能持续恶化。传统治疗方法均未成功,于是构建了一个系统,用于在BPF一侧的胸膜腔内添加可控水平的正压。通过降低呼气时跨肺压差(PEEP减去胸膜腔内压),瘘口漏气显著减少,PEEP和氧合功能得以稳定。该系统可在床边利用大多数医院常规配备的设备迅速构建,并能够在维持PEEP正压通气的同时,调节呼气时跨肺压差、肺容积和BPF气流。