Tomar Sanjeev, Tomar Upma, Singh Richa, Verma Nancy
Department of Oral and Maxillofacial Surgery, Santosh Dental College, Santosh Deemed to be University, Ghaziabad, Uttar Pradesh, India.
Department of Oral and Maxillofacial Pathology and Microbiology, Inderprastha Dental College, Ghaziabad, Uttar Pradesh, India.
J Oral Maxillofac Pathol. 2023 Apr-Jun;27(2):411-415. doi: 10.4103/jomfp.jomfp_7_23. Epub 2023 Jul 13.
Ameloblastoma (AM) is considered one of the most common lesions of odontogenic origin. Although it is always considered as benign neoplasm, ameloblastic carcinoma (AC) represents its malignant counterpart. It is characterized by the expansion of jaws, rapid growth, and a perforated cortex with well-defined unilocular/multilocular radiolucent lesions. To confirm the diagnosis of AM and AC is extremely crucial. Immunohistochemistry such as SOX2 and Ki67 plays a significant role in the confirmation of diagnosis. Management of these cases is from surgical excision with radical neck dissection. The prognosis is poor with only 5 years of survival. This review presents an interesting case of ex-AC, in which the patient was diagnosed at the same site with peripheral AM 1 year ago.
成釉细胞瘤（AM）被认为是最常见的牙源性病变之一。尽管它一直被视为良性肿瘤，但成釉细胞癌（AC）是其恶性对应物。其特征为颌骨膨胀、生长迅速，皮质穿孔，伴有边界清晰的单房/多房透射性病变。确诊AM和AC极其关键。免疫组织化学如SOX2和Ki67在确诊中发挥重要作用。这些病例的治疗方法是手术切除并进行根治性颈清扫。预后较差，生存率仅为5年。本综述介绍了一例有趣的既往AC病例，该患者1年前在同一部位被诊断为外周型AM。
