Banerjee Abhishek, Nandini Doddabasavaiah Basavapur, Misra Satya Ranjan, Chakraborty Bidyut
Department of Oral and Maxillofacial Pathology, Awadh Dental College and Hospital, Jamshedpur, Jharkhand, India.
Department of Oral Pathology and Microbiology, Dental College, Regional Institute of Medical Sciences Imphal, Manipur, India.
J Oral Maxillofac Pathol. 2023 Apr-Jun;27(2):396-398. doi: 10.4103/jomfp.jomfp_313_22. Epub 2023 Jul 13.
Calcifications in the soft tissues can be accidental findings during diagnostic procedures. Oral squamous cell carcinoma (OSCC) forms the major percentage of oral malignancies; calcifications are rare findings in OSCC. Calcifications are seen as a result of necrosis, chronic inflammations as well as degenerative changes and imbalances of the local calcium and phosphorous environment. The presence of calcifications can be a prognostic marker, hypothesizing that the influx of calcium from hard tissues into the soft tissues, can probably determine the invasive nature and the destructive characteristics of the carcinoma; hence, detecting calcifications can help us in predicting the prognosis and spread of the malignancy.
软组织中的钙化可能是诊断过程中的偶然发现。口腔鳞状细胞癌（OSCC）占口腔恶性肿瘤的大部分；钙化在OSCC中是罕见的发现。钙化是坏死、慢性炎症以及局部钙磷环境的退行性变化和失衡的结果。钙化的存在可能是一种预后标志物，推测硬组织中的钙流入软组织可能决定了癌的侵袭性和破坏性特征；因此，检测钙化有助于我们预测恶性肿瘤的预后和扩散。
