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2001-2020 年斯德哥尔摩不同风险特征孕妇的死产发生率:一项重复横断面研究。

Incidence of stillbirth among women with different risk profiles in Stockholm 2001-2020: a repeated cross-sectional study.

机构信息

Department of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.

Department of Obstetrics and Gynecology, Danderyd Hospital, Stockholm, Sweden.

出版信息

Acta Obstet Gynecol Scand. 2024 Jan;103(1):59-67. doi: 10.1111/aogs.14695. Epub 2023 Oct 19.

Abstract

INTRODUCTION

The incidence of stillbirth in Sweden has started to decline. However, some comparable high-income countries in Europe have an even lower incidence, indicating a potential for further reduction. The aim of our study was to investigate how the incidence of stillbirth for singleton pregnancies has changed over the past two decades in the Stockholm Region in different groups of women to detect the groups at highest risk.

MATERIAL AND METHODS

This was a repeated cross-sectional study with data from the Stockholm Stillbirth Database and the Pregnancy Register including all cases of stillbirth in Stockholm in singleton pregnancies between 2001 and 2020, in total 1804 stillbirths. The time period was divided into four equal groups and the incidence of stillbirth was compared between the groups.

RESULTS

The overall incidence of stillbirth in the Stockholm Region has decreased from 3.8/1000 births in 2001-2005 to 2.9/1000 births in 2016-2020 (P-value <0.001). In most of the groups studied, the incidence decreased, but among women originating from sub-Saharan Africa the incidence significantly rose from 7.9/1000 births in 2001-2005 to 10.1/1000 births in 2016-2020 (P-value 0.025). In this group, stillbirth occurred prematurely to a higher extent and the women were more likely to be multiparous.

CONCLUSIONS

The incidence of stillbirth in the Stockholm Region has declined. However, among women originating from sub-Saharan Africa the incidence was significantly higher compared with women originating from other regions and it is still rising. More research is needed to understand why this group is at higher risk and how to monitor their pregnancies to decrease this risk.

摘要

简介

瑞典的死产发生率已开始下降。然而,欧洲一些可比的高收入国家的发生率更低,这表明还有进一步降低的空间。我们的研究目的是调查过去二十年来,在斯德哥尔摩地区不同妇女群体中,单胎妊娠的死产发生率是如何变化的,以发现风险最高的群体。

材料和方法

这是一项重复的横断面研究,数据来自斯德哥尔摩死产数据库和妊娠登记处,包括 2001 年至 2020 年期间斯德哥尔摩所有单胎妊娠死产病例,共 1804 例死产。该时间段分为四个相等的组,比较组间死产发生率。

结果

斯德哥尔摩地区的总死产发生率从 2001-2005 年的 3.8/1000 下降到 2016-2020 年的 2.9/1000(P 值 <0.001)。在所研究的大多数群体中,发生率都有所下降,但来自撒哈拉以南非洲的妇女的发生率显著上升,从 2001-2005 年的 7.9/1000 上升到 2016-2020 年的 10.1/1000(P 值 0.025)。在这个群体中,死产发生的时间更早,且多为多胎妊娠。

结论

斯德哥尔摩地区的死产发生率有所下降。然而,来自撒哈拉以南非洲的妇女的发生率明显高于其他地区的妇女,且仍在上升。需要进一步研究以了解为什么这个群体的风险更高,以及如何监测她们的妊娠以降低这种风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57d0/10755135/4f8c7e4814e9/AOGS-103-59-g002.jpg

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