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上颌牙龈神经鞘瘤:病例报告及文献复习。

Maxillary gingival neurolemmoma: a case report and literature review.

机构信息

Yanbian University Medical College, JiLin, 133000, China.

Stomatology Department, Affiliated Hospital of Yanbian University, JiLin, 133000, China.

出版信息

BMC Oral Health. 2023 Oct 19;23(1):770. doi: 10.1186/s12903-023-03509-7.

Abstract

OBJECTIVE

To explore and summarize the clinical features, differential diagnosis and treatment of the oral maxillofacial schwandoma.

CASE PRESENTATION

This is a report of a case of a 46-year-old female patients with neurolemmoma in the maxillary gingiva. The clinical features, pathological features, differential diagnosis and treatment were analyzed. Literature review was conducted in search of domestic and overseas journal full-text database from 1986 ~ 2017. 39 reports on the oral and maxillofacial Neurolemmoma from 1986 to 2017 in the database of China hospital knowledge database and the PubMed database, there were 405 patients. There were 23 cases of gingival mucosa, 17 in foreign literature and only 6 in the domestic literature.

CONCLUSIONS

The incidence of gingival Neurolemmoma is extremely low, the predilection age is similar to other parts, it is middle-aged and young, and there is no obvious gender tendency. About 25-45% of schwannomas are found in the head and neck, and rarely in the mouth (only 1%). The most common internal location of the mouth is the tongue, followed by the floor of the mouth, buccal mucosa, palate, gums, and lips. Schwannomas are slow-growing benign tumors that are rare in the gums. Gingival schwannoma is usually a single occurrence, and the clinical manifestations are mostly painless gum mass, tooth loosening and displacement, without peripheral bone changes and regional lymph node metastasis. It is difficult to diagnose this tumor according to clinical manifestations, and pathological diagnosis is still the basis for the diagnosis of gingival schwannoma. So far, surgical resection is the preferred treatment for this disease, and the prognosis is good.

摘要

目的

探讨和总结口腔颌面 schwandoma 的临床特征、鉴别诊断和治疗方法。

病例介绍

本文报告了一例 46 岁女性患者,上颌牙龈神经鞘瘤。分析了其临床表现、病理特征、鉴别诊断和治疗。检索 1986 年至 2017 年中国医院知识数据库和 PubMed 数据库国内外期刊全文数据库,共检索到国内口腔颌面神经鞘瘤 39 篇报告,共 405 例患者。牙龈黏膜 23 例,国外文献 17 例,国内文献仅 6 例。

结论

牙龈神经鞘瘤发病率极低,好发年龄与其他部位相似,为中青年人,无明显性别倾向。约 25-45%的神经鞘瘤发生在头颈部,口腔内罕见(仅 1%)。口腔内最常见的内部位置是舌,其次是口底、颊黏膜、 palate、 gums 和 lips。神经鞘瘤是生长缓慢的良性肿瘤,在牙龈中很少见。牙龈 schwannoma 通常为单发,临床表现多为无痛性牙龈肿块、牙齿松动和移位,无周围骨改变和区域性淋巴结转移。根据临床表现诊断该肿瘤较为困难,病理诊断仍是诊断牙龈 schwannoma 的基础。到目前为止,手术切除仍是治疗该病的首选方法,预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/971c/10588195/037526612d14/12903_2023_3509_Fig4_HTML.jpg

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