Alsharif Rafa H, Alhussain Raghad M, Alotaibi Shahad A, Alraihan Jawaher I, Alharbi Ahlam
General Practice, Taibah University, Medina, SAU.
General Practice, Khamis Mushait General Hospital, Aseer, SAU.
Cureus. 2023 Sep 18;15(9):e45497. doi: 10.7759/cureus.45497. eCollection 2023 Sep.
Migraine, a widespread and incapacitating neurological disorder, affects numerous individuals worldwide, causing severe headaches and impairing their quality of life. The interplay of genetic, environmental, and neurovascular factors underlies the pathophysiology of migraine. This report highlights the case of a 25-year-old woman with recurrent, severe headaches, predominantly in the right frontal and temporal regions. She was diagnosed with migraine with aura, a diagnosis supported by her family history. No previous history of seizures was reported. A comprehensive work-up, including neuroimaging, revealed left internal carotid artery hypoplasia with compensatory collateral circulation. The coexistence of severe migraines and left internal carotid artery hypoplasia underscores the complex interrelationship between cerebrovascular anomalies and neurological symptoms. The rarity of this vascular variation emphasizes the need for attentive clinical evaluation and consideration of anatomical deviations in migraine patients. As medical knowledge progresses, further research is essential to unravel the mechanisms connecting vascular anomalies and neurological disorders, ultimately leading to personalized interventions for improved patient outcomes.
偏头痛是一种广泛存在且使人丧失能力的神经系统疾病，影响着全球众多人群，导致严重头痛并损害他们的生活质量。遗传、环境和神经血管因素的相互作用是偏头痛病理生理学的基础。本报告重点介绍了一名25岁女性的病例，她反复出现严重头痛，主要集中在右侧额叶和颞叶区域。她被诊断为伴有先兆的偏头痛，家族病史支持这一诊断。既往无癫痫发作史。包括神经影像学检查在内的全面检查显示左侧颈内动脉发育不全并伴有代偿性侧支循环。严重偏头痛与左侧颈内动脉发育不全并存，凸显了脑血管异常与神经症状之间复杂的相互关系。这种血管变异的罕见性强调了对偏头痛患者进行细致临床评估并考虑解剖学偏差的必要性。随着医学知识的进步，进一步的研究对于阐明连接血管异常与神经系统疾病的机制至关重要，最终实现个性化干预以改善患者预后。
