St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.
Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
Eur J Ophthalmol. 2024 Jan;34(1):287-291. doi: 10.1177/11206721231208998. Epub 2023 Oct 20.
To describe a new method for delivering DMEK grafts into the recipient's eye with endothelium inward configuration using a no-forceps injection technique.
We retrospectively review 11 patients that underwent DMEK surgery at our institution using a no-forceps injection technique. The graft was preloaded into an intraocular lens (IOL) cartridge and connected to an anterior chamber maintainer (ACM). A 5 ml non luer lock syringe was inserted into the other end of the ACM to create a one-flow system. The cartridge was inserted into the posterior end of an injector, and the graft was successfully delivered into the recipient's eye.
Twelve eyes of 11 patients were included. Mean follow-up was 9.16 ± 1.3 months. At baseline, mean best corrected visual acuity (BCVA) was 0.76 ± 0.13 logMAr and mean endothelial cell density (ECD) was 2619.00 ± 115.89 cells/mm. At follow-up, BCVA significantly improved to 0.22 ± 0.05 logMAR ( = 0.003). Although we observed a significant reduction in ECD at follow-up (1688 ± 182.20, = 0.002), our patients lost only 35.69 ± 6.36% of endothelial cells.
Our technique can help surgeons safely deliver an endothelium-in graft into the recipient's eye. The method doesn't require the use of a forceps, minimizing the risk of endothelial cell loss or graft damage.
描述一种使用无镊注射技术将内皮面朝向的 DMEK 移植物递送入受体眼内的新方法。
我们回顾性分析了在我院接受无镊注射技术 DMEK 手术的 11 例患者。将移植物预先装入眼内晶状体(IOL)盒并与前房维持器(ACM)相连。将 5ml 无鲁尔锁注射器插入 ACM 的另一端以创建单流系统。将盒插入注射器的后端,成功将移植物递送入受体眼内。
11 例患者的 12 只眼纳入研究。平均随访 9.16±1.3 个月。基线时,平均最佳矫正视力(BCVA)为 0.76±0.13 logMAR,平均内皮细胞密度(ECD)为 2619.00±115.89 个细胞/mm。随访时,BCVA 显著提高至 0.22±0.05 logMAR( = 0.003)。尽管我们观察到随访时 ECD 显著下降(1688±182.20, = 0.002),但我们的患者仅丢失了 35.69±6.36%的内皮细胞。
我们的技术可以帮助外科医生安全地将内皮面向的移植物递送入受体眼内。该方法无需使用镊,最大限度地降低了内皮细胞丢失或移植物损伤的风险。