Cherniakova Marharyta, Varchenko Victoria, Belikov Konstantin
Department of Analytical Chemistry, State Scientific Institution "Institute for Single Crystals" of National Academy of Sciences of Ukraine, 60 Nauky Ave., 61072, Kharkiv, Ukraine.
School of Chemistry, V.N. Karazin Kharkiv National University, 6 Svobody sq., 61022, Kharkiv, Ukraine.
Chem Rec. 2024 Feb;24(2):e202300267. doi: 10.1002/tcr.202300267. Epub 2023 Oct 20.
In the last 10 years the interest in deep eutectic solvents (DESs) as a new class of green solvents has considerably increased. The emergence of numerous of hydrophobic DESs has stimulated intensive research into their application in extraction technologies, including sample preparation. As the properties of such systems are highly dependent on the properties of their components (hydrogen bond donors and acceptors) and can be finely tuned, DESs can be successfully used for the extraction of both metal ions and organic substances, including biomolecules. Despite the rapidly increasing number of publications on the use of DESs as an extraction medium, including review articles, information on the extraction properties of DESs in terms of their chemical composition has not yet been summarized. This review covers available literature data on the physicochemical properties of menthol-based eutectic solvents and the results of their practical application as an extraction medium. Also, the appropriateness of using the term "DES" for all mixtures with melting points lower than the melting points of their components is discussed.
在过去十年中，作为一类新型绿色溶剂的深度共熔溶剂（DESs）受到的关注大幅增加。众多疏水性DESs的出现激发了对其在萃取技术（包括样品制备）中应用的深入研究。由于此类体系的性质高度依赖于其组分（氢键供体和受体）的性质且可进行精细调节，DESs可成功用于金属离子和有机物质（包括生物分子）的萃取。尽管关于使用DESs作为萃取介质的出版物数量迅速增加，包括综述文章，但尚未对DESs基于其化学组成的萃取性质信息进行总结。本综述涵盖了基于薄荷醇的共熔溶剂的物理化学性质的现有文献数据及其作为萃取介质的实际应用结果。此外，还讨论了将“DES”一词用于所有熔点低于其组分熔点的混合物的适用性。
