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[采用中心降温技术对单纯性大动脉转位患者进行深度低温和心脏循环骤停]

[Deep hypothermia and cardiocirculatory arrest with the technic of central cooling in patients with simple transposition of the great arteries].

作者信息

Menicanti L, Frigiola A, Bedogni A, Faccin G, Negri M, Bianchetti M, Belloli G

出版信息

Pediatr Med Chir. 1986 Mar-Apr;8(2):185-7.

PMID:3786180
Abstract

The deep hypothermia and cardiocirculatory arrest are employed mainly for two reasons; to reduce as much as possible the extra corporeal circulation time in patients more suitable to present the deleterious effects of the by-pass circulation, and to have surgical field completely free from the blood, making easier some surgical procedures. In the classic description of Hykasa the deep hypothermia necessary to have a safe cardiocirculatory arrest is obtained by means of surface cooling and an extracorporeal heat exchanger. In our experience deep hypothermia and cardiocirculatory arrest were achieved only by means of core cooling technique; 64 patients with TGA weighing less than 10 kg were operated upon by this method with a mortality rate of 3.1%. The most important mortality risk factors were associated to the low weight of the patients and to the age. The major criticism against core cooling is represented by the thought that this type of cooling can impair cerebral function. In 2 patients we had neurological complications but were unrelated to the technique. We conclude that, when is necessary to perform a cardiocirculatory arrest, the core cooling deep hypothermia is a good, simple and useful technique, with a low danger of neurological complications.

摘要

采用深低温和心脏循环骤停主要有两个原因

一是尽可能缩短体外循环时间,因为有些患者更易出现体外循环的有害影响;二是使手术视野完全无血,便于一些手术操作。在Hykasa的经典描述中,通过体表降温及体外热交换器可实现安全的心脏循环骤停所需的深低温。根据我们的经验,仅通过核心降温技术就能实现深低温和心脏循环骤停;用这种方法对64例体重小于10千克的大动脉转位患者进行了手术,死亡率为3.1%。最重要的死亡风险因素与患者体重低和年龄有关。对核心降温的主要批评观点认为,这种降温方式可能损害脑功能。我们有2例患者出现神经并发症,但与该技术无关。我们得出结论,当有必要进行心脏循环骤停时,核心降温深低温是一种良好、简单且有用的技术,神经并发症风险低。

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