巨细胞病毒（CMV）血症与抢先治疗和抗病毒预防预防高危供体血清阳性、受体血清阴性肝移植受者 CMV 病的随机试验中长期死亡率的关联。
Association of Cytomegalovirus (CMV) DNAemia With Long-Term Mortality in a Randomized Trial of Preemptive Therapy and Antiviral Prophylaxis for Prevention of CMV Disease in High-Risk Donor Seropositive, Recipient Seronegative Liver Transplant Recipients.
机构信息
Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
出版信息
Clin Infect Dis. 2024 Mar 20;78(3):719-722. doi: 10.1093/cid/ciad643.
Abstract
In a post-hoc analysis of the association of CMV DNAemia with long-term mortality in a randomized trial of CMV preemptive therapy vs. antiviral prophylaxis in D+R- liver transplant recipients, post-intervention CMV DNAemia was associated with increased mortality after adjusting for study arm.
摘要
在一项关于 CMV 抢先治疗与抗病毒预防治疗在 D+R-肝移植受者中的随机试验中，CMV DNA 血症与长期死亡率的关联的事后分析中，调整研究臂后，干预后 CMV DNA 血症与死亡率增加相关。
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