Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA.
JNCI Cancer Spectr. 2023 Oct 31;7(6). doi: 10.1093/jncics/pkad089.
Rapid cycle interventional research can accelerate improvements to cancer care delivery and patient health outcomes by answering multiple questions as part of a single research study. To complement ongoing efforts to increase awareness of and support for rapid cycle interventional research, we conducted a systematic portfolio analysis of research grants funded by the National Cancer Institute on the topic.
We used standard portfolio analytic methods for identifying, coding, and synthesizing rapid cycle interventional research funded by the National Cancer Institute between 2016 and 2022. A codebook was used to standardize assessment of the grants by common study characteristics, intervention topics, and cancer care delivery context.
We identified 26 grants, mostly funded since 2019, as rapid cycle interventional research. Most studies included adult or older adult target populations, used electronic systems for intervention delivery, and focused primarily on testing different components of interventions. Studies also used a range of study designs, intervention content areas, cancer sites, and across the cancer control continuum.
The current portfolio analysis of funded rapid cycle interventional research grants suggests a growing albeit relatively small number of studies in this area. Several efforts are needed to continue to grow this area of research, including training programs, funding opportunities, and strengthening research-practice partnerships. This analysis provides a snapshot of current studies and highlights the opportunity for growing this important area of research to optimize cancer care delivery and improve patient outcomes.
快速循环干预研究可以通过在单个研究中回答多个问题,加速改善癌症护理服务和患者健康结果。为了补充正在进行的提高对快速循环干预研究的认识和支持的努力,我们对美国国立卫生研究院(National Cancer Institute)资助的该主题研究项目进行了系统的组合分析。
我们使用标准的投资组合分析方法,对 2016 年至 2022 年间美国国立卫生研究院资助的快速循环干预研究进行了识别、编码和综合分析。使用代码簿来标准化对赠款的评估,评估标准是常见的研究特征、干预主题和癌症护理服务背景。
我们确定了 26 项赠款,这些赠款大多是在 2019 年之后资助的,作为快速循环干预研究。大多数研究的目标人群是成年人或老年人,使用电子系统进行干预,主要集中在测试干预措施的不同组成部分。研究还使用了一系列研究设计、干预内容领域、癌症部位,并贯穿整个癌症控制连续体。
目前对资助的快速循环干预研究赠款的投资组合分析表明,该领域的研究数量虽然在不断增加,但相对较少。需要采取几项措施来继续发展这一研究领域,包括培训计划、资助机会和加强研究-实践伙伴关系。这项分析提供了当前研究的一个快照,并强调了发展这一重要研究领域的机会,以优化癌症护理服务并改善患者的结果。