酷似支气管中心性肉芽肿病的慢性坏死性肺曲霉病。

Chronic necrotizing pulmonary aspergillosis mimicking bronchocentric granulomatosis.

作者信息

Tron V, Churg A

出版信息

Pathol Res Pract. 1986 Oct;181(5):621-6. doi: 10.1016/S0344-0338(86)80161-3.

Abstract

We present a case of slowly progressive Aspergillus infection occurring in a partially immunocompromised host. The histologic pattern mimicked bronchocentric granulomatosis as seen in allergic bronchopulmonary aspergillosis, but the clinical history, spread of disease in the face of steroid therapy, peculiar granulomatous response to the organisms, and large numbers of organisms present suggest that this was really a case of chronic necrotizing pulmonary aspergillosis. These entities must be distinguished because their therapy, prognosis, and clinical significance are totally different.

摘要

我们报告一例发生在部分免疫功能低下宿主的缓慢进展性曲霉感染病例。组织学表现类似于变应性支气管肺曲霉病中所见的支气管中心性肉芽肿病，但临床病史、面对类固醇治疗时疾病的扩散、对病原体独特的肉芽肿反应以及大量病原体的存在表明，这实际上是一例慢性坏死性肺曲霉病。必须区分这些实体，因为它们的治疗、预后和临床意义完全不同。