Ghosh Shankhaneel, Awuah Wireko Andrew, Bharadwaj Hareesha Rishab, Adebusoye Favour Tope, Ou Yong Brian M, Wellington Jack, Abdul-Rahman Toufik, Ovechkin Denys
Institute of Medical Sciences and SUM Hospital, Bhubaneswar, India.
Sumy State University, Sumy, Ukraine.
J Int Med Res. 2023 Oct;51(10):3000605231204427. doi: 10.1177/03000605231204427.
Intracranial aneurysms, affecting 2%-5% of the population, pose a significant challenge to neurosurgeons due to their potential to cause subarachnoid haemorrhage and high mortality rates. Intraoperative angiography is necessary for effective surgical planning and indocyanine green video angiography (ICG-VA) has emerged as a useful tool for real-time visualization of aneurysmal blood flow, aiding in better planning for potential blood flow and detection of aneurysm remnants. This mini narrative review explores the application of ICG-VA in intracranial aneurysm surgery. Compared with conventional dye-based angiography, ICG-VA is safer, more effective and more cost-effective. It can assess haemodynamic parameters, cerebral flow during temporary artery occlusion, completeness of clipping and patency of branch vessels. However, implementing ICG-VA in low- and middle-income countries presents challenges such as financial constraints, limited access to training and expertise, patient selection and consent issues. Addressing these obstacles requires capacity-building, training programmes for neurosurgeons and multidisciplinary teams, technology transfer, equipment donations, public-private partnerships, continued research and development, reducing conventional dye usage, reducing ICG wastage, exploring mechanisms to reuse ICG dyes and advocating for increased government funding and healthcare budgets.
颅内动脉瘤影响着2%-5%的人群,因其可能导致蛛网膜下腔出血和高死亡率,给神经外科医生带来了重大挑战。术中血管造影对于有效的手术规划是必要的,吲哚菁绿视频血管造影(ICG-VA)已成为实时可视化动脉瘤血流的有用工具,有助于更好地规划潜在血流并检测动脉瘤残余。这篇小型叙述性综述探讨了ICG-VA在颅内动脉瘤手术中的应用。与传统的基于染料的血管造影相比,ICG-VA更安全、更有效且更具成本效益。它可以评估血流动力学参数、临时动脉闭塞期间的脑血流、夹闭的完整性和分支血管的通畅性。然而,在低收入和中等收入国家实施ICG-VA存在诸多挑战,如资金限制、培训和专业知识获取有限、患者选择和知情同意问题。解决这些障碍需要能力建设、针对神经外科医生和多学科团队的培训计划、技术转让、设备捐赠、公私伙伴关系、持续的研发、减少传统染料的使用、减少ICG浪费、探索ICG染料再利用机制以及倡导增加政府资金和医疗保健预算。