SOSS-INTAC：转录和 R 环界面处基因组完整性的新守门员。
SOSS-INTAC: a new gatekeeper of genomic integrity at the interface of transcription and R-loops.
机构信息
Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
出版信息
Mol Cell. 2023 Oct 19;83(20):3593-3595. doi: 10.1016/j.molcel.2023.09.030.
PMID:37863028
Abstract
A recent Nature paper by Xu et al. describes an important link between RNA polymerase II promoter-proximal pausing and genome stability orchestrated by liquid droplet formation to reduce unwanted R-loop accumulation.
摘要
徐等人最近在《自然》杂志上发表的一篇论文描述了 RNA 聚合酶 II 启动子近端暂停与液滴形成协调的基因组稳定性之间的重要联系，以减少不必要的 R 环积累。
Zotero 插件