Choi Su-Hyun, Shim Hye-Won, Lee Hae-Hyoung, Ahn Jin-Soo, Kim Yu-Jin, Shin Soo-Yeon, Lee Jung-Hwan, Choi Yu-Sung
Department of Prosthodontics, College of Dentistry, Dankook University, Cheonan 31116, Republic of Korea.
Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 31116, Republic of Korea; Department of Nanobiomedical Science and BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, Republic of Korea; Mechanobiology Dental Medicine Research Center, Dankook University, Cheonan 31116, Republic of Korea.
J Dent. 2023 Dec;139:104746. doi: 10.1016/j.jdent.2023.104746. Epub 2023 Oct 19.
This study assessed the changes in color stability and biocompatibility of computer-aided design and computer-aided manufacturing (CAD-CAM) glass-ceramics after ultraviolet weathering (UW) aging.
A total of 300 plate-shaped specimens (12.0 × 14.0 × 1.5 mm) were prepared using a leucite-reinforced glass-ceramic (IPS Empress CAD; E), a lithium disilicate (IPS e.max CAD; M), and two zirconia-reinforced lithium silicate (Celtra Duo; C, Vita Suprinity; V) glass-ceramics. Specimens were divided into three groups (n = 25, each), subjected to water storage at 37 °C for 24 h (control group), or UW aging at 150 kJ/m (first-aged group) or 300 kJ/m (second-aged group). The color stability, mechanical and surface properties, and biocompatibility of the CAD-CAM glass-ceramics were investigated experimentally, followed by statistical analysis.
The brightness and redness or greenness were reduced in all groups after aging. After the first aging, V exhibited the largest color change and E exhibited the smallest color change. After the second aging, E exhibited the highest nanoindentation hardness and Young's modulus. The surface roughness was the highest for V after the first aging. Furthermore, the hydrophilicity of the materials increased after aging process. The cell proliferation/viability of human gingival fibroblasts was the highest in E before and after aging. Almost all cells survived for all groups based on a live/dead assay.
Leucite-reinforced glass-ceramic exhibit the highest color stability and biocompatibility after aging. The color stability and biocompatibility of CAD-CAM glass-ceramics depend on the aging process and material type.
Various CAD-CAM glass-ceramics exhibit adequate color stability after UW aging. The leucite-reinforced glass-ceramics exhibit the highest color stability, cell proliferation, and viability after aging. The color stability, mechanical and surface properties, and biocompatibility of the glass-ceramics depend on the aging process and material type.
本研究评估了计算机辅助设计与计算机辅助制造（CAD-CAM）玻璃陶瓷在紫外线老化（UW）后的颜色稳定性和生物相容性变化。
使用白榴石增强玻璃陶瓷（IPS Empress CAD；E）、二硅酸锂（IPS e.max CAD；M）以及两种氧化锆增强硅酸锂（Celtra Duo；C，Vita Suprinity；V）玻璃陶瓷制备了总共300个板状试样（12.0×14.0×1.5mm）。试样分为三组（每组n = 25），分别在37°C下储存24小时（对照组），或在150 kJ/m下进行UW老化（首次老化组）或在300 kJ/m下进行UW老化（二次老化组）。对CAD-CAM玻璃陶瓷的颜色稳定性、机械性能和表面性能以及生物相容性进行了实验研究，随后进行了统计分析。
老化后所有组的亮度以及红色度或绿色度均降低。首次老化后，V的颜色变化最大，E的颜色变化最小。二次老化后，E表现出最高的纳米压痕硬度和杨氏模量。首次老化后V的表面粗糙度最高。此外，老化过程后材料的亲水性增加。人牙龈成纤维细胞的细胞增殖/活力在老化前后E组中最高。基于活/死检测，几乎所有组的细胞都存活。
白榴石增强玻璃陶瓷在老化后表现出最高的颜色稳定性和生物相容性。CAD-CAM玻璃陶瓷的颜色稳定性和生物相容性取决于老化过程和材料类型。
各种CAD-CAM玻璃陶瓷在UW老化后表现出足够的颜色稳定性。白榴石增强玻璃陶瓷在老化后表现出最高的颜色稳定性、细胞增殖和活力。玻璃陶瓷的颜色稳定性、机械性能和表面性能以及生物相容性取决于老化过程和材料类型。
