1990-2019 年中东和北非地区风湿性心脏病负担。

The burden of rheumatic heart disease in the Middle East and North Africa region, 1990-2019.

机构信息

Clinical Research Development Unit of Tabriz-Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran; Clinical Research Development Unit of Tabriz-Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Arch Cardiovasc Dis. 2023 Dec;116(12):542-554. doi: 10.1016/j.acvd.2023.09.005. Epub 2023 Oct 6.

DOI:10.1016/j.acvd.2023.09.005

PMID:37863752

Abstract

BACKGROUND

Rheumatic heart disease (RHD) is a treatable and preventable condition resulting from acute rheumatic fever.

AIM

To report the prevalence, mortality and disability-adjusted life-years (DALY) due to RHD in the Middle East and North Africa (MENA) region from 1990 to 2019, by sex, age group, country and sociodemographic index (SDI).

METHODS

Information on the prevalence, mortality and DALY associated with RHD were obtained from the Global Burden of Disease Study 2019. Data were gathered for all countries in the MENA region over the period 1990-2019. These data included counts and age-standardized rates per 100,000, accompanied by 95% uncertainty intervals (UIs).

RESULTS

The MENA region had an age-standardized point prevalence of 388.9 per 100,000 in 2019, which was 5.4% higher than in 1990. The annual incidence rate was 1.6, which was 63.4% lower than in 1990. There were 379.4 thousand DALY attributable to RHD in 2019, with an age-standardized rate of 67.1, which was 61.3% lower than in 1990. In 2019, an estimated 7.4 thousand deaths were due to RHD, and the age-standardized death rate was 63.4% lower in 2019 than in 1990. DALY rates rose steadily with increasing age in both males and females. The SDI correlated negatively with the rate of DALY for RHD throughout the study period.

CONCLUSION

The burden of RHD in MENA declined from 1990 to 2019, demonstrating the importance of regularly updating health data and identifying risk factors, and developing effective guidelines on prevention.

摘要

背景

风湿性心脏病（RHD）是一种由急性风湿热引起的可治疗和可预防的疾病。

目的

报告 1990 年至 2019 年期间，中东和北非（MENA）地区 RHD 的流行率、死亡率和伤残调整生命年（DALY），按性别、年龄组、国家和社会人口指数（SDI）进行分类。

方法

从 2019 年全球疾病负担研究中获得了与 RHD 相关的流行率、死亡率和 DALY 的信息。数据来自 1990 年至 2019 年期间 MENA 地区的所有国家。这些数据包括每 10 万人的数量和年龄标准化率，以及 95%的置信区间（UI）。

结果

2019 年，MENA 地区的年龄标准化点流行率为每 10 万人 388.9 例，比 1990 年高 5.4%。年发病率为 1.6，比 1990 年低 63.4%。2019 年，归因于 RHD 的 DALY 为 379.4 千例，年龄标准化率为 67.1，比 1990 年低 61.3%。2019 年，估计有 7.4 千人死于 RHD，年龄标准化死亡率比 1990 年低 63.4%。在男性和女性中，DALY 率随着年龄的增长而稳步上升。在整个研究期间，SDI 与 RHD 的 DALY 率呈负相关。