阿尔及利亚单峰驼中存在中东呼吸综合征冠状病毒的血清学初步证据。

First serological evidence of MERS-CoV in dromedary camels from Algeria.

机构信息

Laboratory of Biology and Experimental Pharmacology, University of Medea, Algeria.

Laboratory of Biology and Experimental Pharmacology, University of Medea, Algeria; Department of Biology, Faculty of Sciences, University of Medea, Algeria.

出版信息

Comp Immunol Microbiol Infect Dis. 2023 Dec;103:102078. doi: 10.1016/j.cimid.2023.102078. Epub 2023 Oct 19.

DOI:10.1016/j.cimid.2023.102078

PMID:37865007

Abstract

Middle East Respiratory Syndrome (MERS) is a zoonotic disease. Dromedary camel is responsible of its transmission to humans. Accordingly, several human cases have been reported worldwide with a high mortality rate. In Algeria, no data reported on MERS prevalence in camels. This is a first seroprevalence study MERS-CoV in Algerian dromedaries. A total of 87 camel blood samples from EL -MENIAA and Ghardaia, were analyzed by anti-MERS-CoV IgG ELISA camel. The seroprevalence was 64 % and it significantly increases with age. Larger serological and molecular screening is needed to precisely determine the rate of MERS active circulation among Algerian dromedary population.

摘要

中东呼吸综合征（MERS）是一种人畜共患病。单峰驼是其传播给人类的罪魁祸首。因此，全世界已经报告了几例人类感染病例，死亡率很高。在阿尔及利亚，没有报告关于骆驼中 MERS 流行率的数据。这是对阿尔及利亚单峰驼中 MERS-CoV 的首次血清流行率研究。对来自 EL-MENIAA 和 Ghardaia 的 87 份骆驼血液样本进行了抗 MERS-CoV IgG ELISA 检测。血清阳性率为 64%，且随年龄显著增加。需要进行更大规模的血清学和分子筛查，以准确确定 MERS 在阿尔及利亚单峰驼种群中的活跃传播率。