Maldonado Lauren Y, Bosques Linette, Cromer Sara J, Azar Sharl S, Yu Elaine W, Burnett-Bowie Sherri-Ann M
Department of Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Bigelow 730, Boston, MA 02114, USA; Department of Pediatrics, MassGeneral Hospital for Children and Harvard Medical School, 175 Cambridge Street, Boston, MA 02114, USA.
Department of Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Bigelow 730, Boston, MA 02114, USA.
Endocrinol Metab Clin North Am. 2023 Dec;52(4):629-641. doi: 10.1016/j.ecl.2023.05.004. Epub 2023 Jun 25.
Racial and ethnic disparities exist in the prevalence and management of osteoporosis, metastatic cancer, and sickle cell disease. Despite being the most common metabolic bone disease, osteoporosis remains underscreened and undertreated among Black women. Skeletal-related events in metastatic cancer include bone pain, pathologic fractures, and spinal cord compression. Disparities in screening for and treating skeletal-related events disproportionately affect Black patients. Metabolic bone disease contributes significantly to morbidity in sickle cell disease; however, clinical guidelines for screening and treatment do not currently exist. Clinical care recommendations are provided to raise awareness, close health care gaps, and guide future research efforts.
骨质疏松症、转移性癌症和镰状细胞病的患病率及管理方面存在种族和族裔差异。尽管骨质疏松症是最常见的代谢性骨病，但在黑人女性中，其筛查和治疗仍不足。转移性癌症中的骨相关事件包括骨痛、病理性骨折和脊髓压迫。骨相关事件筛查和治疗方面的差异对黑人患者的影响尤为严重。代谢性骨病在镰状细胞病的发病中起重要作用；然而，目前尚无筛查和治疗的临床指南。本文提供临床护理建议，以提高认识、缩小医疗保健差距并指导未来的研究工作。
