Division of Cardiology, Department of Medicine, University of California Los Angeles (UCLA) Medical Center, Ahmanson/UCLA Adult Congenital Heart Disease Center, Los Angeles, CA, USA; UCLA Cardiac Arrhythmia Center, UCLA Health System, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Division of Cardiology, Department of Pediatrics, UCLA Medical Center, Los Angeles, CA, USA.
Division of Cardiology, Monroe Carell Jr Children's Hospital, Vanderbilt University, 2200 Children's Way, Suite 5230, Nashville, TN 37232, USA.
Card Electrophysiol Clin. 2023 Dec;15(4):457-466. doi: 10.1016/j.ccep.2023.06.009. Epub 2023 Aug 5.
For patients with congenital heart disease (CHD), chronic ventricular pacing may lead to progressive cardiomyopathy owing to electromechanical dyssynchrony. Cardiac conduction system pacing (CSP) has been proposed as a physiologic pacing strategy-directly engaging the His-Purkinje system and preserving electromechanical synchrony. CSP may be indicated for a wide variety of children and adults with CHD and has emerged as an important tool in the armamentarium for cardiac implantable electronic device operators. This review provides the rationale, background, and supportive evidence for CSP in patients with CHD and discusses implant strategies and outcomes in the context of dominant ventricular morphologic categories.
对于患有先天性心脏病(CHD)的患者,由于机电失同步,慢性心室起搏可能导致进行性心肌病。心脏传导系统起搏(CSP)已被提议作为一种生理性起搏策略-直接参与希氏-浦肯野系统并保持机电同步。CSP 可能适用于各种患有 CHD 的儿童和成人,并且已成为心脏植入式电子设备操作人员的重要工具。本综述提供了 CSP 在 CHD 患者中的基本原理、背景和支持性证据,并讨论了在主要心室形态类别背景下的植入策略和结果。