Department of Urology, Montefiore Medical Center, Bronx, NY, USA.
Washington State University Elson S. Floyd College of Medicine, Spokane, WA, USA.
Int J Impot Res. 2024 Apr;36(2):155-159. doi: 10.1038/s41443-023-00781-7. Epub 2023 Oct 21.
Xiaflex® (collagenase clostridium histolyticum) is a Food and Drug Administration-approved treatment for patients with Peyronie's disease. Despite its approval and implementation, there is concern that urologists in training are offered minimal exposure to its use. Thus, the purpose of this study was to evaluate the exposure of urology residents to Peyronie's disease and its management, particularly Xiaflex®. A Google Forms survey regarding the exposure of residents to Peyronie's disease and use of Xiaflex® was created and disseminated through email to urology programs. Overall, 47 institutional responses were received. At 45 institutions (95.7%), residents receive training in directly evaluating and caring for patients with Peyronie's disease. At 46 institutions (97.9%), residents receive training in observing and/or performing surgical procedures for Peyronie's disease. Residents at 31 institutions (66.0%) receive observational or procedural training for non-surgical management of Peyronie's disease, specifically Xiaflex®. Residents receive non-surgical training from an academic faculty who is fellowship trained in sexual medicine at 25 institutions and an academic faculty not trained in sexual medicine at six institutions. There exists a glaring disparity in residency exposure to Xiaflex®. Further research is warranted to elucidate how programs can provide residents with further exposure to the use of Xiaflex® in patients with Peyronie's disease.
Xiaflex®（胶原酶梭菌组织溶菌素）是一种经食品和药物管理局批准的治疗阴茎硬结症的药物。尽管已获得批准并付诸实施，但人们仍担心接受培训的泌尿科医生对其使用的接触非常有限。因此，本研究旨在评估泌尿科住院医师对阴茎硬结症及其管理（尤其是 Xiaflex®）的接触情况。我们创建了一个关于住院医师接触阴茎硬结症和使用 Xiaflex®的 Google 表单调查，并通过电子邮件分发给泌尿科项目。总共收到了 47 个机构的回复。在 45 个机构（95.7%）中，住院医师接受过直接评估和护理阴茎硬结症患者的培训。在 46 个机构（97.9%）中，住院医师接受过观察和/或进行阴茎硬结症手术程序的培训。在 31 个机构（66.0%）中，住院医师接受过阴茎硬结症非手术治疗的观察性或程序性培训，特别是 Xiaflex®。在 25 个机构中，住院医师接受了性医学专科培训的学术教员的非手术培训，在 6 个机构中，住院医师接受了未接受性医学专科培训的学术教员的非手术培训。住院医师接触 Xiaflex®的情况存在明显差异。需要进一步研究阐明计划如何为住院医师提供更多接触 Xiaflex®治疗阴茎硬结症患者的机会。
