State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Respiration. 2023;102(11):961-968. doi: 10.1159/000534352. Epub 2023 Oct 20.
Robotic platforms have been widely used in the various fields of clinical diagnosis and therapy of diseases in the past decade. Robotic-assisted bronchoscopy (RAB) demonstrates its advantages of visibility, flexibility, and stability in comparison to conventional bronchoscopic techniques. Improving diagnostic yield and navigation yield for peripheral pulmonary lesions has been defined; however, RAB platform of treatment was not reported. In this article, we report a case of a 52-year-old woman who was diagnosed with the tracheal adenoid cystic carcinoma and recurred in the second postoperative year, leading to the involvement of the entire tracheal wall and lumen obstruction. Since the lesion was inoperable, we combined RAB and photodynamic therapy (PDT) for the patient. The potential advantages of using RAB for PDT delivery include precise light irradiation of target lesions and stable intra-operative control over the long term. This is a novel application of RAB combined with PDT for airway diseases. The case report may provide a new insight into the diagnosis and treatment of pulmonary diseases. In addition to improving the diagnostic rates, the RAB platform may also play an important role in the treatment of airway and lung disease in the future.
在过去的十年中，机器人平台已广泛应用于临床疾病的诊断和治疗的各个领域。与传统的支气管镜技术相比，机器人辅助支气管镜（RAB）显示出其可视性、灵活性和稳定性的优势。它提高了对周围性肺部病变的诊断和导航的检出率；然而，RAB 平台的治疗效果尚没有报道。在本文中，我们报告了 1 例 52 岁女性患者，该患者被诊断为气管腺样囊性癌，在术后第二年复发，累及整个气管壁和管腔阻塞。由于病变无法手术切除，我们对该患者联合使用 RAB 和光动力疗法（PDT）。使用 RAB 进行 PDT 输送的潜在优势包括对目标病变的精确光照射和对长期的稳定术中控制。这是 RAB 联合 PDT 用于气道疾病的新应用。该病例报告可能为肺部疾病的诊断和治疗提供新的思路。除了提高诊断率外，RAB 平台在未来也可能在气道和肺部疾病的治疗中发挥重要作用。
