Department of Medical Laboratory, Al-Rafidain University College, Baghdad, Iraq.
Department of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.
Int J Biol Macromol. 2023 Dec 31;253(Pt 8):127479. doi: 10.1016/j.ijbiomac.2023.127479. Epub 2023 Oct 20.
The primary objective of this investigation was to synthesize a novel antibacterial nanocomposite consisting of natural gellan gum (GG) hydrogel, MnFe LDH, GO, and FeO nanoparticle, which was developed to adsorb Indigo carmine (IC). The GG hydrogel/MnFe LDH/GO/FeO nanocomposite was characterized through different analytical, microscopic, and biological methods. The results of adsorption experiments reveal that 0.004 g of the nanocomposite can remove 98.38 % of IC from a solution with an initial concentration of 100 mg/L, within 1 h at room temperature and under acidic pH conditions. Moreover, the nanocomposite material effectively suppressed the in vitro growth of both E. coli and S. aureus strains, with inhibitory rates of 62.33 % and 53.82 %, respectively. The isotherm data obtained in this investigation were fitted by linear and non-linear forms of Langmuir, Freundlich, and Dubinin-Radushkevich (D-R) isotherms equations. The results of the adsorption kinetics study indicated that the pseudo-second-order model best described the experimental data. The findings of this study suggest that the synthesized nanocomposites hold great potential as effective adsorbents for removing IC and bacteria from aqueous solutions.
本研究的主要目的是合成一种由天然结冷胶（GG）水凝胶、MnFe LDH、GO 和 FeO 纳米颗粒组成的新型抗菌纳米复合材料，用于吸附靛蓝胭脂红（IC）。通过不同的分析、微观和生物学方法对 GG 水凝胶/MnFe LDH/GO/FeO 纳米复合材料进行了表征。吸附实验结果表明，在室温下、酸性 pH 条件下，0.004 g 的纳米复合材料在 1 h 内可从初始浓度为 100 mg/L 的溶液中去除 98.38%的 IC。此外，纳米复合材料材料有效抑制了大肠杆菌和金黄色葡萄球菌的体外生长，抑制率分别为 62.33%和 53.82%。通过线性和非线性形式的朗缪尔、弗伦德利希和杜宾-拉什科夫斯基（D-R）等温线方程对获得的等温线数据进行了拟合。吸附动力学研究结果表明，准二级模型最能描述实验数据。本研究结果表明，所合成的纳米复合材料作为从水溶液中去除 IC 和细菌的有效吸附剂具有很大的潜力。
