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[佛罗伦萨第10卫生单位下属细菌学与病毒学实验室检测的尿液样本中细菌菌株的分离频率及耐药性]

[Frequency of isolation and drug resistance of bacterial strains from urine samples tested in the Bacteriology and Virology Laboratory of the U.S.L. 10/D in Florence].

作者信息

Pisani L, Bordonaro P, Nicoletti P, Lamanna A

出版信息

Quad Sclavo Diagn. 1986 Mar;22(1):21-36.

PMID:3786667
Abstract

Two thousand five hundred and sixty-eight positive monomicrobic urine samples (from general practice and hospital wards) were examined and isolated strains were tested against various antimicrobial drugs. Our findings showed that urinary-tract infections caused by Escherichia coli were the most common in females, whereas those by Pseudomonas aeruginosa, Proteus rettgeri, Enterobacter species, other difficult Gram-negative rods and Streptococcus faecalis were in total the most common in males. If we compare the strains isolated from general practice with those from the hospital, no significant differences were observed. E. coli strains were the most susceptible to the tested drugs; cefotaxime, amikacin, cefuroxime and ceftazidime were the most effective drugs against Enterobacter species, Ps. aeruginosa, P. rettgeri and Proteus mirabilis. P. mirabilis and Str. faecalis strains isolated in the hospital were more chemo-resistant than those isolated in general practice. Ampicillin and trimethoprim/sulphamethoxazole were less active against E. coli strains isolated from children's departments in comparison with the others.

摘要

对2568份阳性单微生物尿样(来自全科医疗和医院病房)进行了检查,并对分离出的菌株进行了多种抗菌药物测试。我们的研究结果表明,由大肠杆菌引起的尿路感染在女性中最为常见,而由铜绿假单胞菌、雷氏变形杆菌、肠杆菌属、其他难培养革兰氏阴性杆菌和粪肠球菌引起的尿路感染总体上在男性中最为常见。如果我们将从全科医疗中分离出的菌株与从医院中分离出的菌株进行比较,未观察到显著差异。大肠杆菌菌株对测试药物最敏感;头孢噻肟、阿米卡星、头孢呋辛和头孢他啶是对抗肠杆菌属、铜绿假单胞菌、雷氏变形杆菌和奇异变形杆菌最有效的药物。医院中分离出的奇异变形杆菌和粪肠球菌菌株比全科医疗中分离出的菌株更具化学抗性。与其他菌株相比,氨苄西林和甲氧苄啶/磺胺甲恶唑对从儿科分离出的大肠杆菌菌株活性较低。

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