Department of Pediatrics, Emory University and Children's Healthcare of Atlanta, 2015 Uppergate Drive Northeast, Atlanta, GA 30322, USA.
Department of Pediatrics, Emory University and Children's Healthcare of Atlanta, 2015 Uppergate Drive Northeast, Atlanta, GA 30322, USA.
Clin Perinatol. 2023 Dec;50(4):805-820. doi: 10.1016/j.clp.2023.08.001. Epub 2023 Sep 16.
Red blood cell transfusion is common in neonatal intensive care. Multiple trials have evaluated different thresholds for when to administer red blood cell transfusion. In contrast, there has been less focus on studies of the characteristics of red blood cells transfused into neonates. In this review, the authors summarize the emerging literature on the potential impact of the sex of blood donors on outcomes in transfused neonates using a systematic search strategy. The authors review the uncertainty generated from studies with conflicting findings and discuss considerations regarding the impact of blood donor sex and other characteristics on neonatal outcomes.
红细胞输注在新生儿重症监护中很常见。多项试验已经评估了不同的输血阈值。相比之下,对于输注到新生儿体内的红细胞特征的研究关注较少。在这篇综述中,作者使用系统搜索策略总结了关于献血者性别对输血新生儿结局潜在影响的新出现文献。作者回顾了具有相互矛盾发现的研究产生的不确定性,并讨论了关于献血者性别和其他特征对新生儿结局的影响的考虑因素。