Department of Surgery, Tulane University, School of Medicine, New Orleans, LA.
Department of Surgery, Tulane University, School of Medicine, New Orleans, LA.
Surgery. 2024 Jan;175(1):146-152. doi: 10.1016/j.surg.2023.09.025. Epub 2023 Oct 20.
Radiofrequency ablation is a minimally invasive treatment for thyroid nodules; however, concerns exist regarding its impact on subsequent thyroid surgery. We compared surgical outcomes and complications between patients undergoing thyroidectomy after radiofrequency ablation (post-radiofrequency ablation thyroidectomy group) and those without prior radiofrequency ablation (non-radiofrequency ablation thyroidectomy group).
We retrospectively analyzed thyroidectomy patients, comparing post-radiofrequency ablation thyroidectomy and non-radiofrequency ablation thyroidectomy groups, examining demographics, nodule characteristics, surgical techniques, and complications.
The study included 96 patients (73 in the non-radiofrequency ablation thyroidectomy group and 23 in the post-radiofrequency ablation thyroidectomy group). The mean age was 53.3 ± 14.4 years, with 78.1% female patients and 36.5% African American patients. Median operative time was similar between the post-radiofrequency ablation thyroidectomy (110 minutes) and the non-radiofrequency ablation thyroidectomy (92 minutes) cohorts (P = .40). Complications were reported in 13 patients, without significant differences between groups (P = .54). No permanent complications, including nerve injury or hypoparathyroidism, were reported in either cohort. Prior radiofrequency ablation treatment did not increase the risk of complications (odds ratio = 3.48, 95% confidence interval = 0.70-17.43, P = .16).
Our work found no differences in outcomes or safety in patients undergoing thyroidectomy with or without previous radiofrequency ablation treatment, potentiating the post-radiofrequency ablation thyroidectomy group as a safe management option. Accordingly, this may reassure both clinicians and patients of the safety of radiofrequency ablation in treating patients with thyroid nodules.
射频消融术是一种治疗甲状腺结节的微创方法，但人们对其对后续甲状腺手术的影响存在担忧。我们比较了射频消融术后（射频消融术后甲状腺切除术组）和未行射频消融术（非射频消融术甲状腺切除术组）患者的手术结果和并发症。
我们回顾性分析了甲状腺切除术患者，比较了射频消融术后甲状腺切除术和非射频消融术甲状腺切除术组，检查了人口统计学、结节特征、手术技术和并发症。
该研究纳入了 96 例患者（非射频消融术甲状腺切除术组 73 例，射频消融术后甲状腺切除术组 23 例）。患者平均年龄为 53.3±14.4 岁，女性占 78.1%，非裔美国人占 36.5%。射频消融术后甲状腺切除术组（110 分钟）与非射频消融术甲状腺切除术组（92 分钟）的中位手术时间相似（P=0.40）。两组患者的并发症发生率无显著差异（P=0.54）。两组均未报告永久性并发症，包括神经损伤或甲状旁腺功能减退。既往射频消融治疗并未增加并发症的风险（比值比=3.48，95%置信区间=0.70-17.43，P=0.16）。
我们的研究结果表明，对于接受甲状腺切除术的患者，无论是否有先前的射频消融治疗，其结果和安全性均无差异，使射频消融术后甲状腺切除术组成为一种安全的管理选择。因此，这可能使临床医生和患者对射频消融治疗甲状腺结节的安全性更有信心。
