Ruiz Holgado Maria Celeste, Depasupil Joanna Iris, Stracher Michael, Fakioglu Esra, Lew Lily Q
Department of Pediatrics, Flushing Hospital Medical Center, 4500 Parsons Blvd, Flushing, NY 11355, USA.
Department of Orthopedics, Jamaica Hospital Medical Center, 8900 Van Vyck Expressway, Jamaica, NY 11418, USA.
Case Rep Infect Dis. 2023 Oct 12;2023:9597582. doi: 10.1155/2023/9597582. eCollection 2023.
represents an uncommon pathogen in human infections. As a veterinary pathogen, causes canine ear and skin infections. Chronic osteomyelitis is a progressive process characterized by bone destruction and the formation of sequestrum. It may be a sequela of untreated or undertreated acute osteomyelitis or septic arthritis. Descriptions detailing the pathogenicity and virulence of osteomyelitis were limited to a few case reports. Among the three reported cases of osteomyelitis, immunosuppression, malignancy, and recent surgical procedures were comorbidities. Compared to those who are immunosuppressed, immunocompetent individuals are generally not susceptible to uncommon microorganisms. Early detection of osteomyelitis, aggressive appropriate prolonged antimicrobial treatment and a multidisciplinary approach contribute to optimal recovery. We report the first case of chronic osteomyelitis in an immunocompetent adolescent.
是人类感染中一种不常见的病原体。作为一种兽医病原体，可引起犬类耳部和皮肤感染。慢性骨髓炎是一个以骨质破坏和死骨形成为特征的进行性过程。它可能是未经治疗或治疗不充分的急性骨髓炎或化脓性关节炎的后遗症。关于骨髓炎的致病性和毒力的详细描述仅限于少数病例报告。在报告的三例骨髓炎病例中，免疫抑制、恶性肿瘤和近期手术操作是合并症。与免疫抑制人群相比，免疫功能正常的个体通常不易感染不常见的微生物。早期发现骨髓炎、积极适当延长抗菌治疗以及多学科方法有助于实现最佳康复。我们报告了首例免疫功能正常的青少年慢性骨髓炎病例。
