Toyota S, Nakagawa T, Yamaguchi N, Taya K, Higashiguchi T, Kawarada Y
Radioisotopes. 1986 Aug;35(8):423-8. doi: 10.3769/radioisotopes.35.8_423.
Splenectomy is known to increase the risk of bacterial infection. Recently splenic autotransplantation has been suggested as a method of preserving splenic function. In order to demonstrate the viability of transplanted tissue, spleen scintigraphy using 99mTc labeled heat damaged erythrocytes were carried out. So far 21 studies have done in 12 patients. Spleen scans were positive 1 month after surgery, though images showed poor contrast against considerable background of bone marrow and blood pool. The quality of the images much improved five to twelve months after surgery. Functioning splenic autografts could be also shown by scintigraphy using 99mTc sulfur colloid, but the image quality was poorer, particularly within the early stage after operation. Labeling yields were 79.8% on the average, ranging from 45.6-92.3%, that affected little the quality of images. Important techniques in the splenic autotransplantation imaging include a thorough elimination of free 99mTcO4- before injection and to use comparatively small volume of damaged erythrocytes.
脾切除术会增加细菌感染风险。近来，脾自体移植被提议作为一种保留脾脏功能的方法。为了证明移植组织的活力，使用99mTc标记的热损伤红细胞进行了脾脏闪烁扫描。到目前为止，已对12例患者进行了21项研究。术后1个月脾脏扫描呈阳性，不过图像在相当大的骨髓和血池背景下对比度较差。术后5至12个月图像质量有很大改善。使用99mTc硫胶体闪烁扫描也可显示有功能的脾自体移植，但图像质量较差，尤其是在术后早期。标记率平均为79.8%，范围在45.6%至92.3%之间，这对图像质量影响不大。脾自体移植成像的重要技术包括在注射前彻底清除游离的99mTcO4-以及使用相对少量的损伤红细胞。
