Shintani Yasushi, Funaki Soichiro, Kanou Takashi, Ose Naoko, Kimura Toru, Fukui Eriko, Minami Masato, Miyagawa Shigeru
Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
J Thorac Dis. 2023 Sep 28;15(9):5195-5203. doi: 10.21037/jtd-22-1720. Epub 2023 Aug 11.
The first lung transplant procedure in the world was performed in 1983, while in Japan that was first accomplished in 1998. Over the following 25 years, lung transplantation has become a viable treatment option for Japanese patients with a variety of end-stage lung diseases. Seventy cadaveric-donor lung (41 single, 29 bilateral), 11 bilateral living-donor lobar lung, and three heart-lung transplants have been performed with use of an integrated cardiothoracic team approach at medical facilities associated with Osaka University. Extremely advanced clinical and surgical skill sets are required to complete a lung transplant procedure, including surgical knowledge and techniques, as well as management of cardiovascular surgery, especially in regard to mechanical circulatory support (MCS), vascular anastomosis in difficult cases, and concomitant cardiac surgery. We have found that a collaborative effort by general thoracic and cardiac surgeons is an important key for success with lung transplantation. Complex lung transplant surgery and management in Japan are performed by use of an integrated cardiothoracic team approach, which has led to a synergistic impact on successful lung transplantation cases by capitalizing greatly on the experiences, techniques, and expertise of cardiac and thoracic experts. The present review is focused on the role of cardiac surgeons from the viewpoint of our experience with these cases.
世界上第一例肺移植手术于1983年实施,而在日本则于1998年首次完成。在随后的25年里,肺移植已成为日本各种终末期肺病患者的一种可行治疗选择。大阪大学附属医院通过心胸联合团队的方法,已进行了70例尸体供肺移植(41例单肺移植,29例双肺移植)、11例双侧活体供肺叶移植以及3例心肺移植。完成肺移植手术需要极其先进的临床和外科技能,包括外科知识和技术,以及心血管外科的管理,特别是在机械循环支持(MCS)、困难病例的血管吻合以及同期心脏手术方面。我们发现胸外科医生和心脏外科医生的共同努力是肺移植成功的关键。日本复杂的肺移植手术和管理采用心胸联合团队的方法进行,通过充分利用心脏和胸科专家的经验、技术和专业知识,对成功的肺移植病例产生了协同效应。本综述从我们处理这些病例的经验角度,重点关注心脏外科医生的作用。