Nemes Attila, Kormányos Árpád, Ambrus Nóra, Szolnoky Győző, Kemény Lajos
Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Department of Dermatology and Allergology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Quant Imaging Med Surg. 2023 Oct 1;13(10):6590-6597. doi: 10.21037/qims-23-243. Epub 2023 Sep 11.
Lymphedema (LE) is a chronic condition, which refers to tissue swelling due to excess interstitial fluid accumulation or impaired lymphatic conduit. Theoretically, lymphedema-related fluid retention could affect left ventricular (LV) mechanics, which could be detailed by recent three-dimensional speckle-tracking echocardiography. Therefore, it was purposed to examine LV strains in LE patients before and one hour after the use of medical compression stockings and to compare findings to those of matched normal subjects.
The study comprised 26 cases with lymphedema, however, 4 cases had to be excluded due to inferior quality of images. Their results were compared to 27 age- and gender-matched healthy controls.
Global LV circumferential and area strains and mean segmental LV circumferential strain were increased in lymphedema patients before the use of medical compression stockings as compared to controls. One hour after the use of medical compression stockings, no global and mean segmental LV strain showed significant impairment or improvement, but tendentious reduction was seen in LV circumferential strain. With LV segmental analysis, midventricular LV radial, circumferential and area strains proved to be significantly increased, while basal LV longitudinal strain and midventricular LV three-dimensional strain were decreased as compared to controls. No changes in regional LV strains could be detected after one-hour medical compression stockings use as compared to data collected at rest.
Increased global LV circumferential strain is seen in lymphedema. With using medical compression stockings, LV deformation parameters change towards the normal range emphasizing their importance on cardiac function.
淋巴水肿（LE）是一种慢性疾病，指由于间质液过度积聚或淋巴管道受损导致的组织肿胀。理论上，淋巴水肿相关的液体潴留可能影响左心室（LV）力学，这可以通过最近的三维斑点追踪超声心动图详细观察。因此，本研究旨在检查淋巴水肿患者在使用医用弹力袜之前和之后一小时的左心室应变，并将结果与匹配的正常受试者进行比较。
该研究包括26例淋巴水肿患者，但由于图像质量较差，有4例被排除。将他们的结果与27名年龄和性别匹配的健康对照者进行比较。
与对照组相比，淋巴水肿患者在使用医用弹力袜之前，左心室整体圆周应变和面积应变以及平均节段性左心室圆周应变增加。使用医用弹力袜一小时后，没有观察到左心室整体和平均节段性应变有显著损伤或改善，但左心室圆周应变有下降趋势。通过左心室节段分析，与对照组相比，心室中部左心室径向、圆周和面积应变显著增加，而左心室基底纵向应变和心室中部左心室三维应变降低。与静息时收集的数据相比，使用医用弹力袜一小时后，未检测到左心室局部应变的变化。
淋巴水肿患者可见左心室整体圆周应变增加。使用医用弹力袜后，左心室变形参数向正常范围变化，强调了它们对心脏功能的重要性。
