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自体干细胞移植后早期对疫苗可预防感染的血清保护和血清转化高发生率。

High Rates of Seroprotection and Seroconversion to Vaccine-Preventable Infections in the Early Post-Autologous Stem Cell Transplant Period.

作者信息

Hall Victoria G, Saunders Natalie R, Klimevski Emily, Tennakoon Gayani S, Khot Amit, Harrison Simon, Worth Leon J, Yong Michelle K, Slavin Monica A, Teh Benjamin W

机构信息

Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.

Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Australia.

出版信息

Open Forum Infect Dis. 2023 Oct 5;10(10):ofad497. doi: 10.1093/ofid/ofad497. eCollection 2023 Oct.

Abstract

In patients early post-autologous stem cell transplant, seroprotection rates were high for type B and tetanus toxoid (70%-90%) but lower for (30%-50%) including after revaccination. There were high rates of seropositivity (67%-86%) to measles, mumps, and rubella and varicella zoster virus. Durability of protection requires assessment.

摘要

在自体干细胞移植后的早期患者中,B型和破伤风类毒素的血清保护率较高(70%-90%),但包括再次接种后,[此处原文缺失疫苗名称]的血清保护率较低(30%-50%)。对麻疹、腮腺炎、风疹和水痘带状疱疹病毒的血清阳性率较高(67%-86%)。保护的持久性需要评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2774/10588611/f2e68fb1aaa5/ofad497f1.jpg

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