Mine Keisuke, Sakamoto Noriho, Ozasa Mutsumi, Tsutsui Shin, Miyashita Ritsuko, Tokito Takatomo, Okuno Daisuke, Yura Hirokazu, Kido Takashi, Ishimoto Hiroshi, Takemoto Shinnosuke, Takazono Takahiro, Obase Yasushi, Ishimatsu Yuji, Fukuoka Junya, Mukae Hiroshi
Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Department of Radiology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Respir Med Case Rep. 2023 Oct 12;46:101928. doi: 10.1016/j.rmcr.2023.101928. eCollection 2023.
A 63-year-old Japanese woman with multiple cysts in both lungs on chest computed tomography (CT) was referred to our hospital after a thorough examination, including a transbronchial lung biopsy (TBLB), failed to provide a diagnosis. Based on the findings on chest CT and pathological examination of the bronchoalveolar lavage fluid and transbronchial lung cryobiopsy (TBLC) specimen, the patient was diagnosed with pulmonary Langerhans cell histiocytosis (PLCH). TBLC may replace TBLB as the main diagnostic technique for PLCH, although further studies are required to determine the usefulness of TBLC for the diagnosis of PLCH.
一名63岁的日本女性,胸部计算机断层扫描(CT)显示双肺有多个囊肿。在包括经支气管肺活检(TBLB)在内的全面检查未能明确诊断后,她被转诊至我院。根据胸部CT结果以及支气管肺泡灌洗液和经支气管肺冷冻活检(TBLC)标本的病理检查结果,该患者被诊断为肺朗格汉斯细胞组织细胞增多症(PLCH)。尽管需要进一步研究来确定TBLC对PLCH诊断的有效性,但TBLC可能会取代TBLB成为PLCH的主要诊断技术。