理解谱域光学相干断层扫描中的假性视乳头水肿。
Understanding pseudopapilledema on spectral domain optical coherence tomography.
机构信息
Neuroophthalmology Services, Sankara Nethralaya, 18 College Road, Chennai, Tamil Nadu, India.
Comprehensive Ophthalmology, Neuroophthalmology Services, Sankara Nethralaya, 18 College Road, Chennai, Tamil Nadu, India.
出版信息
Indian J Ophthalmol. 2023 Nov;71(11):3552-3557. doi: 10.4103/IJO.IJO_3146_22.
PURPOSE
Optic nerve head drusen (ONHD), peripapillary hyperreflective ovoid mass-like structures (PHOMS), and horizontal hyperreflective lines (HHL) are commonly seen in eyes with pseudopapilledema on enhanced depth imaging (EDI) spectral domain optical coherence tomography (SDOCT). The objective of this study is to assess the frequency of ONHD, PHOMS, and HHL on spectral domain OCT in the eyes diagnosed to have pseudopapilledema.
METHODS
A retrospective case-control study included patients diagnosed as pseudopapilledema and had EDI SD OCT imaging of the optic nerve head (n = 48 eyes) and controls (n = 20 eyes). OCT scans through the optic nerve head were studied to diagnose ONHD, HHL, and PHOMS. One proportion z test was used to find the difference in proportions.
RESULTS
Forty eight eyes of 27 subjects were studied. ONHD as described by the optic disc drusen Studies consortium was noted in 19 eyes (39.48%), P value-0.032, PHOMS in 31 eyes (64.6%), P value 0.043, HL in 19 eyes (39.48%), P value 0.032, and none of the normals had ONHD, PHOMS, and HHL.
CONCLUSIONS
PHOMS are more frequently seen than ONHD and HHL in eyes with pseudopapilledema.
目的
在增强深度成像（EDI）谱域光学相干断层扫描（SDOCT）中，视神经头（ON）出现神经纤维头玻璃疣（ONHD）、神经纤维头旁高反射卵圆形团块样结构（PHOMS）和水平高反射线（HHL）是假性视盘水肿的常见表现。本研究旨在评估在诊断为假性视盘水肿的眼中，SDOCT 上 ONHD、PHOMS 和 HHL 的出现频率。
方法
本回顾性病例对照研究纳入了被诊断为假性视盘水肿且视神经头 EDI SD OCT 成像的患者（n=48 眼）和对照组（n=20 眼）。通过视神经头 OCT 扫描诊断 ONHD、HHL 和 PHOMS。采用单侧比例 z 检验比较比例差异。
结果
共纳入 27 名受试者的 48 只眼。19 只眼（39.48%）出现了视神经盘玻璃疣研究联合会描述的 ONHD，P 值为 0.032；31 只眼（64.6%）出现 PHOMS，P 值为 0.043；19 只眼（39.48%）出现 HHL，P 值为 0.032；而对照组中无一例出现 ONHD、PHOMS 和 HHL。
结论
在假性视盘水肿眼中，PHOMS 比 ONHD 和 HHL 更为常见。
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