Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark -
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark -
Int Angiol. 2023 Dec;42(6):512-519. doi: 10.23736/S0392-9590.23.05103-9. Epub 2023 Oct 23.
Three-dimensional ultrasound (3D-US) and computed tomography (CT) have proven abdominal aortic aneurysm (AAA) volume a more sensitive measure of growth than diameter. This proof-of-concept study aimed to investigate the clinical applicability of two-dimensional ultrasound and 3D-US for AAA diameter and volume growth pattern evaluation.
AAA patients with at least three follow-ups within a minimum of 24 months were included prospectively and consecutively from the COpenhagen Aneurysms CoHort (COACH). Individual diameter and volume growth rates were categorized as rapid, slow, or no growth (>6.0, 3.8-6.0, and ≤3.7 mm/year for diameter. >17.4, 8.8-17.3, and ≤8.7 mL/year for volume). Similarly, diameter and volume growth patterns were categorized as as linear, exponential, staccato, and indeterminate growth, based from individual regressions.
Thirty patients were included, of which 19 (63%) had no diameter growth, 10 (33%) had slow growth, and one (3%) had rapid growth. Regarding volume, 11 (37%) patients had no growth, 12 (40%) had slow growth, and seven (23%) had rapid growth. Growth patterns according to diameter showed that 18 (60%) patients had linear growth, none had staccato or exponential growth. Twelve (40%) were indeterminate. Volume growth patterns found 19 (63%) patients with linear growth, 3 (10%) with staccato, and none with exponential growth. Eight (27%) were indeterminate.
Analysis of AAA volume growth patterns is a practical and safe modality that seems more sensitive at detecting growth patterns than AAA diameter. Volume also detects more AAA growth than diameter.
三维超声（3D-US）和计算机断层扫描（CT）已证明，腹主动脉瘤（AAA）的体积比直径更能敏感地衡量其生长情况。本概念验证研究旨在探讨二维超声和 3D-US 用于评估 AAA 直径和体积生长模式的临床适用性。
前瞻性连续纳入至少有 3 次随访且随访时间至少 24 个月的 COpenhagen Aneurysms CoHort（COACH）AAA 患者。个体直径和体积增长率分为快速、缓慢或无生长（直径>6.0、3.8-6.0 和≤3.7 mm/年；体积>17.4、8.8-17.3 和≤8.7 mL/年）。同样，基于个体回归，将直径和体积生长模式分为线性、指数、间断和不定型生长。
共纳入 30 例患者，其中 19 例（63%）无直径生长，10 例（33%）生长缓慢，1 例（3%）生长迅速。就体积而言，11 例（37%）患者无生长，12 例（40%）生长缓慢，7 例（23%）生长迅速。根据直径的生长模式，18 例（60%）患者呈线性生长，无间断或指数生长。12 例（40%）为不定型。体积生长模式发现 19 例（63%）患者呈线性生长，3 例（10%）呈间断性生长，无指数生长。8 例（27%）为不定型。
AAA 体积生长模式分析是一种实用且安全的方法，似乎比 AAA 直径更能敏感地检测出生长模式。体积也比直径检测到更多的 AAA 生长。
