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Open Forum Infect Dis. 2022 May 3;9(7):ofac218. doi: 10.1093/ofid/ofac218. eCollection 2022 Jul.
2
Antibiotic practice patterns with procalcitonin levels in patients with acute lower respiratory tract infection.降钙素原水平指导下急性下呼吸道感染患者的抗生素应用实践。
Am J Manag Care. 2022 Feb 1;28(2):e35-e41. doi: 10.37765/ajmc.2022.88825.
3
Defining safety net hospitals in the health services research literature: a systematic review and critical appraisal.在卫生服务研究文献中定义安全网医院:一项系统综述与批判性评价
BMC Health Serv Res. 2021 Mar 25;21(1):278. doi: 10.1186/s12913-021-06292-9.
4
Quality improvement time-saving intervention to increase use of a clinical decision support tool to reduce low-value diagnostic imaging in a safety net health system.提高质量以节省时间的干预措施,以增加临床决策支持工具的使用,从而减少在安全网式医疗体系中低价值的诊断性影像学检查。
BMJ Open Qual. 2021 Feb;10(1). doi: 10.1136/bmjoq-2020-001076.
5
Seeking care for back pain or upper respiratory infections?: Survey results to inform a safety net hospital Choosing Wisely® intervention.因背痛或上呼吸道感染寻求治疗?:用于为安全网医院明智选择®干预措施提供信息的调查结果
Healthc (Amst). 2020 Sep;8(3):100424. doi: 10.1016/j.hjdsi.2020.100424. Epub 2020 Jun 12.
6
Antibiotic prescribing without documented indication in ambulatory care clinics: national cross sectional study.在门诊护理诊所中,没有记录在案的指征下开具抗生素处方:全国横断面研究。
BMJ. 2019 Dec 11;367:l6461. doi: 10.1136/bmj.l6461.
7
A Multifaceted Intervention Improves Prescribing for Acute Respiratory Infection for Adults and Children in Emergency Department and Urgent Care Settings.多方面干预措施改善了急诊科和急诊所成人和儿童急性呼吸道感染的处方。
Acad Emerg Med. 2019 Jul;26(7):719-731. doi: 10.1111/acem.13690. Epub 2019 Jun 19.
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Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery at a Safety-Net Health System.评价一项干预措施,以减少在一个保障型医疗体系中接受白内障手术的患者的低价值术前护理。
JAMA Intern Med. 2019 May 1;179(5):648-657. doi: 10.1001/jamainternmed.2018.8358.
9
Appropriateness of outpatient antibiotic prescribing among privately insured US patients: ICD-10-CM based cross sectional study.美国私人保险患者门诊抗生素处方适宜性:基于 ICD-10-CM 的横断面研究。
BMJ. 2019 Jan 16;364:k5092. doi: 10.1136/bmj.k5092.
10
Changes to Racial Disparities in Readmission Rates After Medicare's Hospital Readmissions Reduction Program Within Safety-Net and Non-Safety-Net Hospitals.医保医院再入院率削减计划实施后,医保安全网内和非安全网内医院入院率的种族差异变化。
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选择明智的干预措施来减少安全网中抗生素的过度使用。

Choosing Wisely interventions to reduce antibiotic overuse in the safety net.

机构信息

Division of General Internal Medicine & Health Services Research, Department of Internal Medicine, David Geffen School of Medicine at UCLA, 1100 Glendon Ave, Ste 726, Los Angeles, CA 90024. Email:

出版信息

Am J Manag Care. 2023 Oct;29(10):488-496. doi: 10.37765/ajmc.2023.89367.

DOI:10.37765/ajmc.2023.89367
PMID:37870542
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10994234/
Abstract

OBJECTIVES

Physician pay-for-performance (P4P) programs frequently target inappropriate antibiotics. Yet little is known about P4P programs' effects on antibiotic prescribing among safety-net populations at risk for unintended harms from reducing care. We evaluated effects of P4P-motivated interventions to reduce antibiotic prescriptions for safety-net patients with acute respiratory tract infections (ARTIs).

STUDY DESIGN

Interrupted time series.

METHODS

A nonrandomized intervention (5/28/2015-2/1/2018) was conducted at 2 large academic safety-net hospitals: Los Angeles County+University of Southern California (LAC+USC) and Olive View-UCLA (OV-UCLA). In response to California's 2016 P4P program to reduce antibiotics for acute bronchitis, 5 staggered Choosing Wisely-based interventions were launched in combination: audit and feedback, clinician education, suggested alternatives, procalcitonin, and public commitment. We also assessed 5 unintended effects: reductions in Healthcare Effectiveness Data and Information Set (HEDIS)-appropriate prescribing, diagnosis shifting, substituting antibiotics with steroids, increasing antibiotics for ARTIs not penalized by the P4P program, and inappropriate withholding of antibiotics.

RESULTS

Among 3583 consecutive patients with ARTIs, mean antibiotic prescribing rates for ARTIs decreased from 35.9% to 22.9% (odds ratio [OR], 0.60; 95% CI, 0.39-0.93) at LAC+USC and from 48.7% to 27.3% (OR, 0.81; 95% CI, 0.70-0.93) at OV-UCLA after the intervention. HEDIS-inappropriate prescribing rates decreased from 28.9% to 19.7% (OR, 0.69; 95% CI, 0.39-1.21) at LAC+USC and from 40.9% to 12.5% (OR, 0.72; 95% CI, 0.59-0.88) at OV-UCLA. There was no evidence of unintended consequences.

CONCLUSIONS

These real-world multicomponent interventions responding to P4P incentives were associated with substantial reductions in antibiotic prescriptions for ARTIs in 2 safety-net health systems without unintended harms.

摘要

目的

医生薪酬与表现(P4P)计划经常针对不当使用抗生素。然而,对于 P4P 计划对面临因减少医疗而产生不良后果风险的安全网人群的抗生素处方开具的影响,人们知之甚少。我们评估了 P4P 激励干预措施对急性呼吸道感染(ARTI)安全网患者抗生素处方的影响。

研究设计

中断时间序列。

方法

在 2 家大型学术性安全网医院(洛杉矶县+南加州大学[LAC+USC]和奥利弗观-UCLA[OV-UCLA])进行了一项非随机干预(2015 年 5 月 28 日至 2018 年 2 月 1 日)。为响应加利福尼亚州 2016 年的 P4P 计划,减少急性支气管炎的抗生素使用,我们联合开展了 5 项基于明智选择的干预措施:审核和反馈、临床医生教育、替代方案建议、降钙素原和公开承诺。我们还评估了 5 种意外后果:医疗保健效果数据和信息集(HEDIS)适当处方减少、诊断转移、用类固醇替代抗生素、增加 P4P 计划未处罚的 ARTI 的抗生素使用、以及不适当的抗生素停药。

结果

在 3583 例连续 ARTI 患者中,LAC+USC 的抗生素治疗率从 35.9%降至 22.9%(比值比[OR],0.60;95%置信区间[CI],0.39-0.93),OV-UCLA 从 48.7%降至 27.3%(OR,0.81;95% CI,0.70-0.93)。在 LAC+USC,HEDIS 不适当处方率从 28.9%降至 19.7%(OR,0.69;95% CI,0.39-1.21),OV-UCLA 从 40.9%降至 12.5%(OR,0.72;95% CI,0.59-0.88)。没有证据表明存在意外后果。

结论

这些针对 P4P 激励措施的真实世界多因素干预措施与 2 个安全网卫生系统中 ARTI 抗生素处方的大量减少相关,而无意外伤害。