Lazzarini Peter A, Raspovic Anita, Prentice Jenny, Commons Robert J, Fitridge Robert A, Charles James, Cheney Jane, Purcell Nytasha, Twigg Stephen M
Queensland University of Technology, Brisbane, QLD.
Allied Health Research Collaborative, Metro North Hospital and Health Service, Brisbane, QLD.
Med J Aust. 2023 Nov 20;219(10):485-495. doi: 10.5694/mja2.52136. Epub 2023 Oct 23.
Diabetes-related foot disease (DFD) - foot ulcers, infection, ischaemia - is a leading cause of hospitalisation, disability, and health care costs in Australia. The previous 2011 Australian guideline for DFD was outdated. We developed new Australian evidence-based guidelines for DFD by systematically adapting suitable international guidelines to the Australian context using the ADAPTE and GRADE approaches recommended by the NHMRC.
This article summarises the most relevant of the 98 recommendations made across six new guidelines for the general medical audience, including: prevention - screening, education, self-care, footwear, and treatments to prevent DFD; classification - classifications systems for ulcers, infection, ischaemia and auditing; peripheral artery disease (PAD) - examinations and imaging for diagnosis, severity classification, and treatments; infection - examinations, cultures, imaging and inflammatory markers for diagnosis, severity classification, and treatments; offloading - pressure offloading treatments for different ulcer types and locations; and wound healing - debridement, wound dressing selection principles and wound treatments for non-healing ulcers.
For people without DFD, key changes include using a new risk stratification system for screening, categorising risk and managing people at increased risk of DFD. For those categorised at increased risk of DFD, more specific self-monitoring, footwear prescription, surgical treatments, and activity management practices to prevent DFD have been recommended. For people with DFD, key changes include using new ulcer, infection and PAD classification systems for assessing, documenting and communicating DFD severity. These systems also inform more specific PAD, infection, pressure offloading, and wound healing management recommendations to resolve DFD.
糖尿病相关足部疾病(DFD)——足部溃疡、感染、缺血——是澳大利亚住院、残疾和医疗保健费用的主要原因。2011年之前的澳大利亚DFD指南已过时。我们采用澳大利亚国家健康与医学研究理事会(NHMRC)推荐的ADAPTE和GRADE方法,通过系统地使合适的国际指南适用于澳大利亚的情况,制定了新的基于证据的澳大利亚DFD指南。
本文为普通医学受众总结了六项新指南中98条建议中最相关的内容,包括:预防——筛查、教育、自我护理、鞋类以及预防DFD的治疗方法;分类——溃疡、感染、缺血的分类系统及审核;外周动脉疾病(PAD)——诊断、严重程度分级及治疗的检查和成像;感染——诊断、严重程度分级及治疗的检查、培养、成像和炎症标志物;减压——针对不同溃疡类型和部位的减压治疗;以及伤口愈合——清创、伤口敷料选择原则和不愈合溃疡的伤口治疗。
对于没有DFD的人,关键变化包括使用新的风险分层系统进行筛查、对风险进行分类以及管理DFD风险增加的人群。对于那些被归类为DFD风险增加的人,建议采取更具体的自我监测、鞋类处方、手术治疗和活动管理措施来预防DFD。对于患有DFD的人,关键变化包括使用新的溃疡、感染和PAD分类系统来评估、记录和传达DFD的严重程度。这些系统还为解决DFD提供了更具体的PAD、感染、减压和伤口愈合管理建议。