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糖尿病相关足部感染住院患者的主要病原体:澳大利亚视角

Is the Predominant Pathogen in Hospitalised Patients with Diabetes-Related Foot Infections: An Australian Perspective.

作者信息

Morton Kate E, Coghill Sarah H

机构信息

Pharmacy Department, Lismore Base Hospital, Lismore, NSW 2480, Australia.

Infectious Diseases Department, Lismore Base Hospital, Lismore, NSW 2480, Australia.

出版信息

Antibiotics (Basel). 2024 Jun 26;13(7):594. doi: 10.3390/antibiotics13070594.

Abstract

Diabetes prevalence continues to increase worldwide, which has led to a rising incidence of diabetes-related foot infections (DFIs). There is significant local variation in the microbiology of DFIs, and spp. is suggested to be more prevalent in subtropical climates. The aim of this study was to investigate the local microbiological findings in patients admitted to the hospital with DFIs. This retrospective study analysed data from all adult patients diagnosed with diabetes and admitted to the hospital for the treatment of a DFI between 1 January 2021 and 31 December 2022. Both superficial wound swabs and tissue cultures were included. The Infectious Diseases Society of America classification system was used to categorise the severity of the DFI. Patient characteristics and demographics were analysed using descriptive statistics. One hundred fifty-one episodes of care were included. Most of the DFIs were classified as moderate infections 101/151 (67%). The most commonly isolated microorganism was (33%) followed by normal skin flora (11%) and β-haemolytic streptococci (7%). was isolated more commonly in those with chronic DFIs (10%) compared to those with acute DFIs (2%). Despite the frequent identification of , 83% of patients received an antipseudomonal antibiotic. The introduction of multidisciplinary DFI rounds should be considered.

摘要

全球糖尿病患病率持续上升,这导致糖尿病相关足部感染(DFIs)的发病率不断增加。DFIs的微生物学存在显著的局部差异,并且某菌属在亚热带气候中更为普遍。本研究的目的是调查因DFIs入院患者的局部微生物学结果。这项回顾性研究分析了2021年1月1日至2022年12月31日期间所有被诊断为糖尿病并因DFIs入院治疗的成年患者的数据。纳入了浅表伤口拭子和组织培养样本。采用美国传染病学会分类系统对DFIs的严重程度进行分类。使用描述性统计分析患者特征和人口统计学数据。共纳入151例护理事件。大多数DFIs被分类为中度感染101/151(67%)。最常分离出的微生物是某菌(33%),其次是正常皮肤菌群(11%)和β溶血性链球菌(7%)。与急性DFIs患者(2%)相比,慢性DFIs患者中某菌的分离率更高(10%)。尽管经常鉴定出某菌,但83%的患者接受了抗假单胞菌抗生素治疗。应考虑引入多学科DFIs会诊。

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