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新发1型糖尿病合并糖尿病酮症酸中毒患儿的脂血血清：一例报告

Lipemic Serum in a Child With New-Onset Type 1 Diabetes Mellitus Presenting With Diabetic Ketoacidosis: A Case Report.

作者信息

Hansa Christina, Vijayakumar Vimalraj, Chinnasami Balaji, Sundar Subash

机构信息

Department of Paediatrics, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chennai, IND.

出版信息

Cureus. 2023 Sep 22;15(9):e45777. doi: 10.7759/cureus.45777. eCollection 2023 Sep.

DOI:10.7759/cureus.45777
PMID:37872901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10590602/
Abstract

Diabetic ketoacidosis (DKA) was observed in a 12-year-old female child recently diagnosed with type 1 diabetes mellitus. A rise in triglyceride (TG) levels accompanied this. High TG levels were suspected due to the lipemic appearance of the serum. Acute pancreatitis and lipemia retinalis are potential complications for hypertriglyceridemia patients. Treating the DKA and insulin deficiency reverted the TG levels to normal without using lipid-lowering agents.

摘要

一名最近被诊断为1型糖尿病的12岁女童出现了糖尿病酮症酸中毒（DKA）。同时伴有甘油三酯（TG）水平升高。由于血清呈现脂血外观，怀疑TG水平升高。急性胰腺炎和视网膜脂血症是高甘油三酯血症患者的潜在并发症。在未使用降脂药物的情况下，治疗DKA和胰岛素缺乏使TG水平恢复正常。

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本文引用的文献

1
Diabetic lipemia as a predisposing state to acute pancreatitis: a case report and literature review.糖尿病脂血症作为急性胰腺炎的一种易感状态：一例病例报告及文献综述
Diabetol Int. 2023 Apr 29;14(3):304-311. doi: 10.1007/s13340-023-00630-4. eCollection 2023 Jul.
2
New-Onset Type 1 Diabetes in a Child With Diabetic Ketoacidosis and Severe Hypertriglyceridemia Without Pancreatitis.一名患有糖尿病酮症酸中毒和严重高甘油三酯血症且无胰腺炎的儿童新发1型糖尿病。
JCEM Case Rep. 2023 May 8;1(3):luad046. doi: 10.1210/jcemcr/luad046. eCollection 2023 May.
3
ISPAD clinical practice consensus guidelines 2022: Diabetic ketoacidosis and hyperglycemic hyperosmolar state.
国际儿童青少年糖尿病研究学会（ISPAD）2022年临床实践共识指南：糖尿病酮症酸中毒和高血糖高渗状态
Pediatr Diabetes. 2022 Nov;23(7):835-856. doi: 10.1111/pedi.13406.
4
Severe hypertriglyceridemia: A rare complication of diabetic ketoacidosis in a 3-year-old with SARS-CoV-2 infection.严重高甘油三酯血症：一名3岁感染新型冠状病毒的患儿糖尿病酮症酸中毒的罕见并发症。
J Clin Transl Endocrinol Case Rep. 2021 Dec;22:100099. doi: 10.1016/j.jecr.2021.100099. Epub 2021 Nov 4.
5
Diabetic Ketoacidosis Revealing a Severe Hypertriglyceridemia and Acute Pancreatitis in Type 1 Diabetes Mellitus.糖尿病酮症酸中毒揭示1型糖尿病患者存在严重高甘油三酯血症及急性胰腺炎
Case Rep Endocrinol. 2019 Jan 6;2019:8974619. doi: 10.1155/2019/8974619. eCollection 2019.
6
Severe hypertriglyceridemia at new onset type 1 diabetes mellitus.新发1型糖尿病伴严重高甘油三酯血症。
J Pediatr Endocrinol Metab. 2017 Aug 28;30(8):893-897. doi: 10.1515/jpem-2017-0008.
7
DKA with Severe Hypertriglyceridemia and Cerebral Edema in an Adolescent Boy: A Case Study and Review of the Literature.一名青少年男性糖尿病酮症酸中毒合并严重高甘油三酯血症及脑水肿：病例报告与文献综述
Case Rep Endocrinol. 2016;2016:7515721. doi: 10.1155/2016/7515721. Epub 2016 Jan 20.
8
Severe Hypertriglyceridemia Causing Acute Pancreatitis in a Child with New Onset Type I Diabetes Mellitus Presenting in Ketoacidosis.严重高甘油三酯血症在新发1型糖尿病酮症酸中毒患儿中引发急性胰腺炎。
J Pediatr Intensive Care. 2013;2(2):77-80. doi: 10.3233/PIC-13053.