Thiruvalluru Rohith Kumar, Olfson Mark, Keyes Katherine M, Weissman Myrna M, Pathak Jyoti, Xiao Yunyu
medRxiv. 2024 Aug 2:2023.09.29.23296176. doi: 10.1101/2023.09.29.23296176.
The study aims to quantify differential trends in emergency, outpatient, and inpatient healthcare service utilization among among 2,540,348 patients with and without severe mental illness (SMI) before (January 2017 - December 2019) and during (January 2020 - April 2022) the COVID-19 pandemic, across three distinct cohorts tracked from January 2017 to April 2022, based on their SMI status.
DESIGN & SETTING: A retrospective cohort study was conducted, utilizing data from Healthix, the second-largest health information exchange in the U.S.
The study population included 2,540,348 patients were categorized by their SMI status as of January 2017 to December 2019 into three groups: Severe Mental Illness 137,801 (5.4%), Other Mental Illness 685,280 (27%), No Mental Illness 1,717,267 (67.6%).
The primary exposure was the COVID-19 pandemic, with a focus on its impact on mental health and non mental health services.
The primary outcome was the rate of utilization of mental health and non mental health services.
Among the non-SMI patients, there was a 30% decline in emergency visits from 650,000 pre-COVID to 455,000 post-COVID (OR=0.70, p < 0.001), and outpatient visits decreased by 50% from 1.2 million to 600,000 (OR=0.50, p = 0.002). In contrast, the SMI group witnessed a 20% reduction in outpatient visits from 120,000 to 96,000 (OR=0.80, p = 0.015) and a 40% decrease in inpatient visits from 50,000 to 30,000 (OR=0.60, p = 0.008). Recurrent SMI patients exhibited a 25% decline in emergency visits from 32,000 to 24,000 (OR=0.75, p = 0.03) and a 35% drop in outpatient visits from 40,000 to 26,000 (OR=0.65, p = 0.009).The pandemic influenced the type of disorders diagnosed. Non-SMI patients experienced a 23% rise in anxiety-related disorders (n=80,000, OR=1.23, p = 0.01) and an 18% increase in stress-related disorders (n=70,000, OR=1.18, p = 0.04). SMI patients had a 15% surge in severe anxiety disorders (n=9,000, OR=1.15, p = 0.02) and a 12% uptick in substance-related disorders (n=7,200, OR=1.12, p = 0.05). Recurrent SMI patients showed a 20% increase in anxiety and adjustment disorders (n=6,400, OR=1.20, p = 0.03).SMI patients were more adversely affected by COVID-19, with a higher infection rate of 7.8% (n=45,972) compared to 4.2% (n=131,669) in non-SMI patients (OR=1.88, p < 0.001). Hospitalization rates also followed this trend, with 5.2% (n=30,648) of SMI patients being hospitalized compared to 3.7% (n=115,995) among non-SMI patients (OR=1.41, p = 0.007). Moreover, SMI patients had lower vaccination rates of 45.6% (n=268,888) versus 58.9% (n=1,844,261) among non-SMI patients (OR=0.77, p = 0.019).
In conclusion, our findings reveal significant disparities in healthcare service utilization between individuals with Serious Mental Illness (SMI) and those without. Notably, the SMI cohort experienced greater disruptions in service continuity, with a more pronounced decline in both outpatient and inpatient visits. Furthermore, the types of disorders diagnosed among this group also saw a shift, emphasizing the need for specialized care and attention during times of crisis. The higher rates of COVID-19 infection and hospitalization among SMI patients compared to non-SMI patients underscore the urgency of targeted public health interventions for this vulnerable group. The lower vaccination rates in the SMI cohort highlight another layer of healthcare disparity that needs to be urgently addressed. These findings suggest that the pandemic has amplified pre-existing inequalities in healthcare access and outcomes for individuals with SMI, calling for immediate, evidence-based interventions to mitigate these effects and ensure equitable healthcare service provision.
本研究旨在量化2540348名患有和未患有严重精神疾病(SMI)的患者在2019年1月至12月之前以及2020年1月至2022年4月新冠疫情期间,基于其SMI状态在三个不同队列(从2017年1月追踪至2022年4月)中的急诊、门诊和住院医疗服务利用的差异趋势。
进行了一项回顾性队列研究,利用美国第二大健康信息交换平台Healthix的数据。
研究人群包括2540348名患者,他们根据2017年1月至2019年12月的SMI状态被分为三组:严重精神疾病患者137801名(5.4%),其他精神疾病患者685280名(27%),无精神疾病患者1717267名(67.6%)。
主要暴露因素是新冠疫情,重点关注其对心理健康和非心理健康服务的影响。
主要结局是心理健康和非心理健康服务的利用率。
在非SMI患者中,急诊就诊次数从新冠疫情前的65万次下降了30%至疫情后的45.5万次(OR=0.70,p<0.001),门诊就诊次数从120万次减少了50%至60万次(OR=0.50,p=0.002)。相比之下,SMI组门诊就诊次数从12万次减少了20%至9.6万次(OR=0.80,p=0.015),住院就诊次数从5万次减少了40%至3万次(OR=0.60,p=0.008)。复发性SMI患者急诊就诊次数从3.2万次下降了25%至2.4万次(OR=0.75,p=0.03),门诊就诊次数从4万次下降了35%至2.6万次(OR=0.65,p=0.009)。疫情影响了诊断出的疾病类型。非SMI患者焦虑相关疾病增加了23%(n=80000,OR=1.23,p=0.01),应激相关疾病增加了18%(n=70000,OR=1.18,p=0.04)。SMI患者严重焦虑疾病增加了15%(n=9000,OR=1.15,p=0.02),物质相关疾病增加了12%(n=7200,OR=1.12,p=0.05)。复发性SMI患者焦虑和适应障碍增加了20%(n=6400,OR=1.20,p=0.03)。SMI患者受新冠疫情的负面影响更大,感染率为7.8%(n=45972),高于非SMI患者的4.2%(n=131669)(OR=1.88,p<0.001)。住院率也呈现这一趋势,SMI患者住院率为5.2%(n=30648),高于非SMI患者的3.7%(n=115995)(OR=1.41,p=0.007)。此外,SMI患者疫苗接种率较低,为45.6%(n=268888),而非SMI患者为58.9%(n=1844261)(OR=0.77,p=0.019)。
总之,我们的研究结果揭示了严重精神疾病(SMI)患者和非SMI患者在医疗服务利用方面存在显著差异。值得注意的是,SMI队列在服务连续性方面受到的干扰更大,门诊和住院就诊次数下降更为明显。此外,该组诊断出的疾病类型也发生了变化,这凸显了在危机时期提供专门护理和关注的必要性。与非SMI患者相比,SMI患者的新冠感染率和住院率更高,这凸显了针对这一弱势群体进行有针对性的公共卫生干预的紧迫性。SMI队列中较低的疫苗接种率凸显了另一个急需解决的医疗保健差距层面。这些发现表明,疫情加剧了SMI患者在医疗服务可及性和治疗结果方面预先存在的不平等,呼吁立即采取基于证据的干预措施来减轻这些影响,并确保公平的医疗服务提供。