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[膀胱副神经节瘤——一种罕见但需鉴别的相关诊断]

[Paraganglioma of the urinary bladder-a rare, but relevant differential diagnosis].

作者信息

Vos Nicolas, Minner Jörg, Böhm Joachim

机构信息

Abteilung für Urologie und Kinderurologie, Hegau-Bodensee-Klinikum Singen, Virchowstr. 10, 78462, Singen, Deutschland.

Institut für Pathologie, Hegau-Bodensee-Klinikum Singen, Singen, Deutschland.

出版信息

Urologie. 2024 Feb;63(2):168-170. doi: 10.1007/s00120-023-02221-2. Epub 2023 Oct 24.

Abstract

A paranglioma is a rare, extra-adrenal neuroendocrine tumour. Paraganglioma of the urinary bladder is very rare, accounting for < 1% of all paranglioma and only 0.05% of all bladder tumours. Presentation varies greatly and its clinical significance is dependent on the tumour functionality. Since paranglioma may look histologically very similar to urothelial carcinomas, the risk of misdiagnosis is relatively high, with considerable therapeutic and medicolegal consequences. This case describes an incidental paraganglioma of the urinary bladder, diagnosed cystoscopically due to painless microhaematuria and confirmed histologically after performing several immunohistochemical examinations.

摘要

副神经节瘤是一种罕见的肾上腺外神经内分泌肿瘤。膀胱副神经节瘤极为罕见,占所有副神经节瘤的不到1%,仅占所有膀胱肿瘤的0.05%。其表现差异很大,临床意义取决于肿瘤的功能状态。由于副神经节瘤在组织学上可能与尿路上皮癌非常相似,误诊风险相对较高,会带来相当大的治疗和法医学后果。本病例描述了一例偶然发现的膀胱副神经节瘤,因无痛性微血尿经膀胱镜检查诊断,并在进行多次免疫组化检查后经组织学确诊。

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