Fil'ko V N, Gorodetskiĭ V M, Gorshkov M P, Kardanova N K, Martynov S V
Ter Arkh. 1986;58(9):122-3.
Modern drug therapy failed to reduce the number of unfavourable outcomes in acute pneumonia. Therefore study of the host responsiveness which plays a crucial role in the course and outcome of pneumonia is showing promise. Disturbed homeostasis, endogenous intoxication, bacteremia and, as a consequence, secondary immunodeficiency make it necessary to look for new treatment methods. The authors suggest the use of plasmapheresis in combined therapy of acute pneumonia running its course in association with pronounced intoxication because of deranged immunity. In emergency cases, the use of intermittent plasmapheresis that requires minimal time for preparation and unsophisticated equipment appears the most acceptable.
现代药物治疗未能减少急性肺炎中不良结局的数量。因此，对在肺炎病程和结局中起关键作用的宿主反应性的研究显示出了前景。内环境稳态紊乱、内源性中毒、菌血症以及由此导致的继发性免疫缺陷使得有必要寻找新的治疗方法。作者建议在因免疫紊乱而伴有明显中毒症状的急性肺炎联合治疗中使用血浆置换术。在紧急情况下，使用所需准备时间最短且设备简单的间歇性血浆置换术似乎是最可接受的。
