Shang Wenwen, Hong Guohui, Li Wei
Department of Medical Imaging, Jiangsu Vocational College of Medicine, Yancheng, China.
Front Oncol. 2023 Oct 9;13:1194128. doi: 10.3389/fonc.2023.1194128. eCollection 2023.
We aimed to review the available evidence on the diagnostic performance of magnetic resonance imaging in differentiating malignant from benign small renal masses.
An electronic literature search of Web of Science, MEDLINE (Ovid and PubMed), Cochrane Library, EMBASE, and Google Scholar was performed to identify relevant articles up to 31 January 2023. We included studies that reported the diagnostic accuracy of using magnetic resonance imaging to differentiate small (≤4 cm) malignant from benign renal masses. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio were calculated using the bivariate model and the hierarchical summary receiver operating characteristic model. The study quality evaluation was performed with the Quality Assessment of Diagnostic Accuracy Studies-2 tool.
A total of 10 studies with 860 small renal masses (815 patients) were included in the current meta-analysis. The pooled sensitivity and specificity of the studies for the detection of malignant masses were 0.85 (95% CI 0.79-0.90) and 0.83 (95% CI 0.67-0.92), respectively.
MRI had a moderate diagnostic performance in differentiating small malignant renal masses from benign ones. Substantial heterogeneity was observed between studies for both sensitivity and specificity.
我们旨在回顾磁共振成像在鉴别肾小肿块良恶性诊断性能方面的现有证据。
对科学网、MEDLINE（Ovid和PubMed）、Cochrane图书馆、EMBASE和谷歌学术进行电子文献检索，以识别截至2023年1月31日的相关文章。我们纳入了报告使用磁共振成像鉴别小（≤4 cm）肾恶性肿块与良性肿块诊断准确性的研究。使用双变量模型和分层汇总接受者操作特征模型计算合并敏感度、特异度、阳性似然比、阴性似然比和诊断比值比。采用诊断准确性研究质量评估-2工具进行研究质量评估。
本荟萃分析共纳入10项研究，涉及860个肾小肿块（815例患者）。这些研究检测恶性肿块的合并敏感度和特异度分别为0.85（95%CI 0.79-0.90）和0.83（95%CI 0.67-0.92）。
磁共振成像在鉴别肾小恶性肿块与良性肿块方面具有中等诊断性能。在敏感度和特异度方面，各研究之间均观察到显著的异质性。
