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Cyclosporine and analogues: structural requirements for immunosuppressive activity.

作者信息

Wenger R

出版信息

Transplant Proc. 1986 Dec;18(6 Suppl 5):213-8.

PMID:3787710
Abstract
摘要

相似文献

1
Cyclosporine and analogues: structural requirements for immunosuppressive activity.
Transplant Proc. 1986 Dec;18(6 Suppl 5):213-8.
2
Synthesis of ciclosporin and analogues: structural and conformational requirements for immunosuppressive activity.
Prog Allergy. 1986;38:46-64.
3
Cyclosporine: conformation and analogues as tools for studying its mechanism of action.环孢素：作为研究其作用机制工具的构象与类似物
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4
Cyclosporins. Structure-activity relationships.环孢菌素。构效关系。
Ann N Y Acad Sci. 1993 Nov 30;696:47-53.
5
Cyclosporine and analogues--isolation and synthesis--mechanism of action and structural requirements for pharmacological activity.环孢素及其类似物——分离与合成——作用机制及药理活性的结构要求
Fortschr Chem Org Naturst. 1986;50:123-36. doi: 10.1007/978-3-7091-8888-0_4.
6
Cyclosporine A in contrast to a cyclosporine metabolite (OL-17) specifically inhibits growth of renal cells in culture.与环孢素代谢物（OL-17）相比，环孢素A特异性抑制培养的肾细胞生长。
Transplant Proc. 1988 Jun;20(3 Suppl 3):732-7.
7
Comparison of the pharmacological profiles of cyclosporine, (Nva2)-cyclosporine and (Val2)dihydro-cyclosporine.环孢素、（Nva2）-环孢素和（Val2）-二氢环孢素的药理学特征比较。
Immunology. 1985 Jun;55(2):249-55.
8
The effect of cyclosporine G (OG37-325), cyclosporine A, and their metabolites on the release of vasoactive substances from primary renal cell lines.环孢素G（OG37 - 325）、环孢素A及其代谢产物对原代肾细胞系释放血管活性物质的影响。
Transplant Proc. 1994 Oct;26(5):3002-5.
9
Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity.环孢菌素：抗血吸虫特性与亲环蛋白异构酶活性抑制之间缺乏相关性。
Exp Parasitol. 1998 Sep;90(1):103-9. doi: 10.1006/expr.1998.4307.
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Design, synthesis and identification of novel colchicine-derived immunosuppressant.新型秋水仙碱衍生免疫抑制剂的设计、合成与鉴定
Bioorg Med Chem Lett. 2009 Aug 1;19(15):4416-20. doi: 10.1016/j.bmcl.2009.05.054. Epub 2009 May 18.

引用本文的文献

1
Molecular aspects of cyclophilins mediating therapeutic actions of their ligands.环孢素结合蛋白介导其配体治疗作用的分子方面。
Cell Mol Life Sci. 2010 Oct;67(20):3467-88. doi: 10.1007/s00018-010-0437-0. Epub 2010 Jul 4.
2
1H and 13C-NMR and molecular dynamics studies of cyclosporin a interacting with magnesium(II) or cerium(III) in acetonitrile. Conformational changes and cis-trans conversion of peptide bonds.环孢菌素A在乙腈中与镁（II）或铈（III）相互作用的1H和13C核磁共振及分子动力学研究。肽键的构象变化和顺反异构化。
Biophys J. 2006 Feb 15;90(4):1350-61. doi: 10.1529/biophysj.105.074245. Epub 2005 Nov 18.
3
Cyclosporin analogs inhibit in vitro growth of Cryptosporidium parvum.
环孢菌素类似物可抑制微小隐孢子虫的体外生长。
Antimicrob Agents Chemother. 1998 Apr;42(4):843-8. doi: 10.1128/AAC.42.4.843.
4
Characterization of anti-Toxoplasma activity of SDZ 215-918, a cyclosporin derivative lacking immunosuppressive and peptidyl-prolyl-isomerase-inhibiting activity: possible role of a P glycoprotein in Toxoplasma physiology.环孢素衍生物SDZ 215-918的抗弓形虫活性特征：缺乏免疫抑制和肽基脯氨酰异构酶抑制活性：P糖蛋白在弓形虫生理学中的可能作用
Antimicrob Agents Chemother. 1997 Sep;41(9):1859-66. doi: 10.1128/AAC.41.9.1859.
5
Dosage, timing, and route of administration of cyclosporin A and nonimmunosuppressive derivatives of dihydrocyclosporin A and cyclosporin C against Schistosoma mansoni in vivo and in vitro.环孢素A以及二氢环孢素A和环孢素C的非免疫抑制衍生物针对曼氏血吸虫的体内和体外给药剂量、时间及途径
Antimicrob Agents Chemother. 1987 Oct;31(10):1567-71. doi: 10.1128/AAC.31.10.1567.
6
The influence of cyclosporin A on cell-mediated immunity.环孢素A对细胞介导免疫的影响。
Clin Exp Immunol. 1988 Mar;71(3):369-76.